1-(4-Methoxyphenyl)-3,4-dihydroisoquinoline

Base Information

Chemical Name:1-(4-Methoxyphenyl)-3,4-dihydroisoquinoline
CAS No.:59224-73-6
Molecular Formula:C16H15NO
Molecular Weight:237.301
Hs Code.:
DSSTox Substance ID:DTXSID30483201
Nikkaji Number:J3.099.238E
Wikidata:Q82320319
Mol file:59224-73-6.mol

Synonyms:1-(4-Methoxyphenyl)-3,4-dihydroisoquinoline;59224-73-6;Isoquinoline, 3,4-dihydro-1-(4-methoxyphenyl)-;SCHEMBL12567716;DTXSID30483201

Suppliers and Price of 1-(4-Methoxyphenyl)-3,4-dihydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-(4-Methoxyphenyl)-3,4-dihydroisoquinoline

Chemical Property:

PSA：21.59000
LogP:2.52430
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:237.115364102
Heavy Atom Count:18
Complexity:304

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NCCC3=CC=CC=C32

Technology Process of 1-(4-Methoxyphenyl)-3,4-dihydroisoquinoline

There total 13 articles about 1-(4-Methoxyphenyl)-3,4-dihydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1262841-97-3
C₂₃H₂₃NO₃S

: 59224-73-6
1-(4'-methoxylphenyl)-3,4-dihydroisoquinoline

Guidance literature:: With sodium hydroxide; In water; dimethyl sulfoxide; at 70 ℃; for 2h; regiospecific reaction;
DOI:10.1080/00397911.2011.568659

Reference yield: 89.0%

: 59224-73-6
1-(4'-methoxylphenyl)-3,4-dihydroisoquinoline

Guidance literature:: With potassium phosphate tribasic trihydrate; palladium on activated charcoal; oxygen; In acetonitrile; at 60 ℃;

Reference yield: 82.0%

: 14157-05-2
1-(methylsulfanyl)-3,4-dihydroisoquinoline

: 5720-07-0
4-methoxyphenylboronic acid

: 59224-73-6
1-(4'-methoxylphenyl)-3,4-dihydroisoquinoline

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) thiophene-2-carboxylate; In tetrahydrofuran; for 1h; Inert atmosphere; Reflux;
DOI:10.1055/s-0034-1379109