7-Chloro-3-phenyl-1H-quinolin-2-one

Base Information

Chemical Name:7-Chloro-3-phenyl-1H-quinolin-2-one
CAS No.:59412-07-6
Molecular Formula:C15H10ClNO
Molecular Weight:255.703
Hs Code.:
ChEMBL ID:CHEMBL423646
DSSTox Substance ID:DTXSID90483803
Wikidata:Q82321406
Mol file:59412-07-6.mol

Synonyms:59412-07-6;7-Chloro-3-phenyl-1H-quinolin-2-one;CHEMBL423646;7-Chloro-2-hydroxy-3-phenylquinoline;7-CHLORO-3-PHENYL-2-QUINOLINOL;3-phenyl-7-chloro-2-quinolone;SCHEMBL11187166;DTXSID90483803;CAPOPJHZFVWDLK-UHFFFAOYSA-N;BDBM50056646;MFCD09997967;7-chloro-1,2-dihydro-2-oxo-3-phenylquinoline

Suppliers and Price of 7-Chloro-3-phenyl-1H-quinolin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 7-Chloro-3-phenyl-1H-quinolin-2-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:459.704oC at 760 mmHg
Flash Point:231.821oC
PSA：33.12000
Density:1.303g/cm3
LogP:4.26080
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:255.0450916
Heavy Atom Count:18
Complexity:360

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC3=C(C=C(C=C3)Cl)NC2=O

Technology Process of 7-Chloro-3-phenyl-1H-quinolin-2-one

There total 12 articles about 7-Chloro-3-phenyl-1H-quinolin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 5551-11-1
4-Chloro-2-nitrobenzaldehyde

: 100-44-7
benzyl chloride

: 59412-07-6
7-chloro-3-phenylquinolin-2(1H)-one

Guidance literature:: With palladium diacetate; magnesium sulfate; 1,8-diazabicyclo[5.4.0]undec-7-ene; bis[2-(diphenylphosphino)phenyl] ether; molybdenum hexacarbonyl; In 1,2-dimethoxyethane; at 100 ℃; for 30h; Inert atmosphere; Sealed tube;
DOI:10.1016/j.mcat.2021.111842

Reference yield: 95.0%

: 4596-92-3
5-chloro-2,1-benzoisoxazole

: 100-44-7
benzyl chloride

: 13939-06-5,199620-15-0
molybdenum hexacarbonyl

: 59412-07-6
7-chloro-3-phenylquinolin-2(1H)-one

Guidance literature:: With water; palladium diacetate; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); triethylamine; In 1,2-dimethoxyethane; at 100 ℃; for 26h; Sealed tube; Inert atmosphere;
DOI:10.1039/d1ob00298h

Reference yield: 65.0%

: 260783-80-0
N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate

: 5551-11-1
4-Chloro-2-nitrobenzaldehyde

: 13939-06-5,199620-15-0
molybdenum hexacarbonyl

: 59412-07-6
7-chloro-3-phenylquinolin-2(1H)-one

Guidance literature:: With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In acetonitrile; at 130 ℃; for 24h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.1c01984