1,1'-(2-Fluoroprop-1-ene-1,1-diyl)dibenzene

Base Information

• Chemical Name: 1,1'-(2-Fluoroprop-1-ene-1,1-diyl)dibenzene
• CAS No.: 59888-13-0
• Molecular Formula: C15H13F
• Molecular Weight: 212.267
• DSSTox Substance ID: DTXSID50565230
• Nikkaji Number: J443.866C
• Mol file: 59888-13-0.mol

Synonyms:59888-13-0;SCHEMBL7639343;DTXSID50565230;1,1'-(2-Fluoroprop-1-ene-1,1-diyl)dibenzene

Chemical Property of 1,1'-(2-Fluoroprop-1-ene-1,1-diyl)dibenzene

Chemical Property:

• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 212.100128577
• Heavy Atom Count: 16
• Complexity: 222

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C(C1=CC=CC=C1)C2=CC=CC=C2)F

Technology Process of 1,1'-(2-Fluoroprop-1-ene-1,1-diyl)dibenzene

There total 9 articles about 1,1'-(2-Fluoroprop-1-ene-1,1-diyl)dibenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(2,2-difluorocyclopropane-1,1-diyl)dibenzene (51954-17-7) → (2-fluoroprop-1-ene-1,1-diyl)dibenzene (59888-13-0)

Guidance literature:

With C₂₄H₂₂FN₃NiO₂; dimethylamine borane; In ⁽²⁾H₈-toluene; at 80 ℃; for 16h; Reagent/catalyst;

DOI:10.1039/c5cc08950f

Reference yield: 80.0%

bromobenzene (108-86-1,52753-63-6) + potassium (E)-(2-fluoro-1-phenylprop-1-en-1-yl)trifluoroborate → (2-fluoroprop-1-ene-1,1-diyl)dibenzene (59888-13-0) + (Z)-(1-fluoro-2-methyl-2-phenylethenyl)benzene (1493-87-4)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tert-butylamine; In water; isopropyl alcohol; at 80 ℃; for 16h; Inert atmosphere;

DOI:10.1021/acs.orglett.8b02195

Reference yield: 75.0%

1,1-diphenylprop-1-en-2-yl trifluoromethanesulfonate (29571-19-5) → (2-fluoroprop-1-ene-1,1-diyl)dibenzene (59888-13-0)

Guidance literature:

With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; C₅₃H₇₃O₂P; cesium fluoride; In 2-methyltetrahydrofuran; at 110 ℃; for 12h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1002/anie.201608927

upstream raw materials:

(+)-(R)-1-fluoro-2,2-diphenylcyclopropanecarbonyl chloride

(R)-(-)-1-Fluoro-1-iodo-2,2-diphenylcyclopropane

1,1-diphenyl-1-propene

benzophenone