1-(3,4-Dihydro-2H-1-benzopyran-3-yl)-4-phenylpiperazine

Base Information

• Chemical Name: 1-(3,4-Dihydro-2H-1-benzopyran-3-yl)-4-phenylpiperazine
• CAS No.: 83823-52-3
• Molecular Formula: C₁₉H₂₂N₂O
• Molecular Weight: 294.396
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID401003908
• Mol file: 83823-52-3.mol

Synonyms:1-(3,4-Dihydro-2H-1-benzopyran-3-yl)-4-phenylpiperazine;83823-52-3;BRN 4489594;Piperazine, 1-(3,4-dihydro-2H-1-benzopyran-3-yl)-4-phenyl-;DTXSID401003908;LS-111548

Chemical Property of 1-(3,4-Dihydro-2H-1-benzopyran-3-yl)-4-phenylpiperazine

Chemical Property:

• Vapor Pressure: 3.19E-08mmHg at 25°C
• Boiling Point: 448.1°C at 760 mmHg
• Flash Point: 133°C
• PSA: 15.71000
• Density: 1.16g/cm³
• LogP: 2.81520
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 294.173213330
• Heavy Atom Count: 22
• Complexity: 347

Purity/Quality:

1-(3,4-DIHYDRO-2H-1-BENZOPYRAN-3-YL)-4-PHENYLPIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CCN1C2CC3=CC=CC=C3OC2)C4=CC=CC=C4

Technology Process of 1-(3,4-Dihydro-2H-1-benzopyran-3-yl)-4-phenylpiperazine

There total 1 articles about 1-(3,4-Dihydro-2H-1-benzopyran-3-yl)-4-phenylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chroman-3-one (19090-04-1) + 4-phenyl-1-piperazine (92-54-6) → 1-Chroman-3-yl-4-phenyl-piperazine (83823-52-3)

Guidance literature:

With hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; Yield given. Multistep reaction; 1) benzene, 4-5h, reflux 2) EtOH;

upstream raw materials:

chroman-3-one

4-phenyl-1-piperazine