(2R)-2-(Dibenzylamino)propan-1-ol

Base Information

• Chemical Name: (2R)-2-(Dibenzylamino)propan-1-ol
• CAS No.: 60479-64-3
• Molecular Formula: C17H21NO
• Molecular Weight: 255.36
• Hs Code.: 2922199090
• DSSTox Substance ID: DTXSID30553094
• Wikidata: Q82433599
• Mol file: 60479-64-3.mol

Synonyms:60479-64-3;2-(R)-Dibenzylaminopropan-1-ol;(2R)-2-(Dibenzylamino)propan-1-ol;(R)-2-(dibenzylamino)propan-1-ol;(-)-N,N-DIBENZYL-D-ALANINOL;SCHEMBL6054336;DTXSID30553094;IEEFFKXJADVWJO-OAHLLOKOSA-N;MFCD07809538;AKOS024386563;BS-44630;CS-0158186;D80272;A1-00442

Chemical Property of (2R)-2-(Dibenzylamino)propan-1-ol

Chemical Property:

• PSA: 23.47000
• LogP: 3.06960
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 255.162314293
• Heavy Atom Count: 19
• Complexity: 211

Purity/Quality:

99%, ^*data from raw suppliers

(R)-2-(Dibenzylamino)propan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CO)N(CC1=CC=CC=C1)CC2=CC=CC=C2
• Isomeric SMILES: C[C@H](CO)N(CC1=CC=CC=C1)CC2=CC=CC=C2

Technology Process of (2R)-2-(Dibenzylamino)propan-1-ol

There total 10 articles about (2R)-2-(Dibenzylamino)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.3%

(R)-2-aminopropan-1-ol (35320-23-1) + benzyl bromide (100-39-0) → 2(R)--1-propanol (60479-64-3)

Guidance literature:

With potassium carbonate; In acetonitrile; at 0 - 20 ℃;

DOI:10.1021/ol4013537

Reference yield: 80.0%

(R)-benzyl 2-(dibenzylamino)-propanoate (668436-83-7) → 2(R)--1-propanol (60479-64-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1016/j.ejmech.2011.09.010

Reference yield:

methyl (R)-2-(N,N-dibenzylamino)propanoate (188798-80-3) → 2(R)--1-propanol (60479-64-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 12h;

DOI:10.1021/jm020164l

upstream raw materials:

(R)-2-(N,N-dibenzylamino)propanoic acid

methyl (R)-2-(N,N-dibenzylamino)propanoate

(R)-2-aminopropan-1-ol

benzyl bromide

Downstream raw materials:

N<1(R)-methyl-2-(3-phenylpropoxy)ethyl>-N-(phenylmethyl)benzenemethaneamine

(R)-2-(dibenzylamino)propanal

N,N-dibenzyl-4-aminopentan-3-ol

(3R*,4R*,5S*)-5-(Dibenzylamino)-3-methyl-1-hexen-4-ol