3-Chloro-N-methyl-2-nitroaniline

Base Information

Chemical Name:3-Chloro-N-methyl-2-nitroaniline
CAS No.:60498-57-9
Molecular Formula:C7H7ClN2O2
Molecular Weight:186.598
Hs Code.:
DSSTox Substance ID:DTXSID40507109
Wikidata:Q82363152

Synonyms:3-Chloro-N-methyl-2-nitroaniline;60498-57-9;Benzenamine, 3-chloro-N-methyl-2-nitro-;(3-Chloro-2-nitro-phenyl)-methyl-amine;SCHEMBL1848788;DTXSID40507109;ZMBXPFROSLWNDZ-UHFFFAOYSA-N;WS-02378;E72160;EN300-7431596

Suppliers and Price of 3-Chloro-N-methyl-2-nitroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Chloro-N-methyl-2-nitroaniline

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:186.0196052
Heavy Atom Count:12
Complexity:171

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=C(C(=CC=C1)Cl)[N+](=O)[O-]

Technology Process of 3-Chloro-N-methyl-2-nitroaniline

There total 6 articles about 3-Chloro-N-methyl-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.6%

: 59483-54-4
3-chloro-2-nitro-aniline

: 77-78-1
dimethyl sulfate

: 60498-57-9
3-chloro-N-methyl-2-nitroaniline

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In water; toluene; for 6h;

Reference yield:

: C₇H₇ClN₂O₃

: 60498-57-9
3-chloro-N-methyl-2-nitroaniline

Guidance literature:: C₇H₇ClN₂O₃; With sodium tris(acetoxy)borohydride; In dichloromethane;

With acetic acid; In dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 59483-54-4
3-chloro-2-nitro-aniline

: 74-88-4
methyl iodide

: 60498-57-9
3-chloro-N-methyl-2-nitroaniline

: 141816-10-6
3-chloro-2-nitro-N,N-dimethylaniline

Guidance literature:: 3-chloro-2-nitro-aniline; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.166667h;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 1h; Overall yield = 550 mg;
DOI:10.1016/j.tetlet.2019.151078