Z-D-GLA(OTBU)2-OH

Base Information

• Chemical Name: Z-D-GLA(OTBU)2-OH
• CAS No.: 60686-52-4
• Molecular Formula: C₂₂H₃₁NO₈
• Molecular Weight: 437.49
• Mol file: 60686-52-4.mol

Synonyms:

Chemical Property of Z-D-GLA(OTBU)2-OH

Chemical Property:

• Storage Temp.: -15°C

Purity/Quality:

99% ^*data from raw suppliers

Z-D-Gla(OtBu)2-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Z-D-GLA(OTBU)2-OH

There total 25 articles about Z-D-GLA(OTBU)2-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(2S)-2-(2-benzyloxycarbonylamino-3-hydroxypropyl)malonic acid di-tert-butyl ester (912354-37-1) → N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamic acid (60686-50-2,60686-52-4)

Guidance literature:

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium chlorite; In phosphate buffer; acetonitrile; at 40 ℃; for 18h; pH=6.7;

DOI:10.1021/jo061037q

Reference yield: 90.0%

Z-γ,γ,-di-tert-butyl-D,L-carboxyglutamic acid methyl ester (56877-40-8) → N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-D-γ-carboxyglutamic acid (56877-43-1,60686-52-4)

Guidance literature:

With diothiothreitol; papain; In N,N-dimethyl-formamide; at 25 ℃; for 20h; pH=6.17 (mellvaine phosphate/citrate buffer 0.1 M containing 1.5 mM of EDTA);

DOI:10.1016/0040-4039(95)02175-2

Reference yield: 76.0%

Z-γ,γ,-di-tert-butyl-D,L-carboxyglutamic acid methyl ester (56877-40-8) → Z-DL-Gla(OtBu)2-OH (56877-43-1,60686-52-4)

Guidance literature:

With potassium hydroxide; In methanol; for 2h; Ambient temperature;

DOI:10.1002/prac.19973390182

upstream raw materials:

Z-DL-Gla(OtBu)2-OH

Z-γ,γ,-di-tert-butyl-D,L-carboxyglutamic acid methyl ester

(2S)-2-(2-benzyloxycarbonylamino-3-hydroxypropyl)malonic acid di-tert-butyl ester

2S-(3-benzyloxycarbonyl-2,2-dimethyloxazolidin-4-ylmethylene)-malonic acid di-tert-butyl ester

Downstream raw materials:

Z-(D)Glu(OtBu)(γ-COOtBu)-Leu-OBzl

N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamic acid

N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-D-γ-carboxyglutamic acid

D(-)-γ-Carboxy-glutaminsaeure

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 60686-52-4 Z-D-GLA(OTBU)2-OH

Send

Send

Metric Ton KG G Pound L ML

Send

Send