Methyl 5-Iodo-2-methoxy-3-methylbenzoate

Base Information

Chemical Name:Methyl 5-Iodo-2-methoxy-3-methylbenzoate
CAS No.:6082-99-1
Molecular Formula:C10H11IO3
Molecular Weight:306.1
Hs Code.:
DSSTox Substance ID:DTXSID60472522
Nikkaji Number:J1.598.262D

Synonyms:Methyl 5-Iodo-2-methoxy-3-methylbenzoate;6082-99-1;SCHEMBL4878432;DTXSID60472522;WDJMTFJSUYVZOP-UHFFFAOYSA-N

Suppliers and Price of Methyl 5-Iodo-2-methoxy-3-methylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 5-Iodo-2-methoxy-3-methylbenzoate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:305.97529
Heavy Atom Count:14
Complexity:208

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1OC)C(=O)OC)I

Technology Process of Methyl 5-Iodo-2-methoxy-3-methylbenzoate

There total 4 articles about Methyl 5-Iodo-2-methoxy-3-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 40912-75-2
2-hydroxy-5-iodo-3-methylbenzoic acid methyl ester

: 77-78-1
dimethyl sulfate

: 6082-99-1
5-iodo-2-methoxy-3-methylbenzoic acid methyl ester

Guidance literature:: With potassium carbonate; In acetone; for 24h; Heating;
DOI:10.1021/jo0100291

Reference yield:

: 83-40-9
3-methylsalicylic acid

: 6082-99-1
5-iodo-2-methoxy-3-methylbenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: tetrabutylammonium bromide; aq. potassium carbonate / CH₂Cl₂ / 4 h / 20 °C

2: sodium iodide; sodium hydroxide; aq. sodium hypochlorite / methanol / 4.5 h / 0 - 3 °C

3: 7.69 g / tetrabutylammonium bromide; aq. sodium hydroxide / CH₂Cl₂ / 20 °C

With sodium hydroxide; sodium hypochlorite; tetrabutylammomium bromide; potassium carbonate; sodium iodide; In methanol; dichloromethane;
DOI:10.1021/jm050452s

Reference yield:

: 23287-26-5
3-methylsalicylic acid methyl ester

: 6082-99-1
5-iodo-2-methoxy-3-methylbenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium iodide; sodium hydroxide; aq. sodium hypochlorite / methanol / 4.5 h / 0 - 3 °C

2: 7.69 g / tetrabutylammonium bromide; aq. sodium hydroxide / CH₂Cl₂ / 20 °C

With sodium hydroxide; sodium hypochlorite; tetrabutylammomium bromide; sodium iodide; In methanol; dichloromethane;
DOI:10.1021/jm050452s