Didemethyl Curcumin

Base Information

Chemical Name:Didemethyl Curcumin
CAS No.:60831-46-1
Molecular Formula:C19H16O6
Molecular Weight:340.332
Hs Code.:
NSC Number:687843
UNII:V9WSK3JJL2
DSSTox Substance ID:DTXSID40873735
Nikkaji Number:J825.014F,J877.765I
Wikidata:Q81981225
ChEMBL ID:CHEMBL319488
Mol file:60831-46-1.mol

Synonyms:Didemethyl Curcumin;60831-46-1;Di-O-demethylcurcumin;DIDEMETHYLCURCUMIN;V9WSK3JJL2;Bis(3,4-Dihydroxy-trans-cinnamoyl)methane;bisdemethylcurcumin;UNII-V9WSK3JJL2;NSC687843;(1E,6E)-1,7-Bis(3,4-dihydroxyphenyl)-1,6-heptadiene-3,5-dione;LI01008;LI-01008;CHEMBL319488;1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dihydroxyphenyl)-, (1E,6E)-;(1E,6E)-1,7-bis(3,4-dihydroxyphenyl)hepta-1,6-diene-3,5-dione;1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dihydroxyphenyl)-, (E,E)-;SCHEMBL613666;SCHEMBL613667;DTXSID40873735;BDBM50059988;BDBM50067030;NSC-687843;(1E,6E)-1,7-Bis-(3,4-dihydroxy-phenyl)-hepta-1,6-diene-3,5-dione;1,7-Bis-(3,4-dihydroxy-phenyl)-5-hydroxy-hepta-1,4,6-trien-3-one;(1E,4Z,6E)-1,7-bis(3,4-dihydroxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one;(1E,4Z,6E)-1,7-Bis-(3,4-dihydroxy-phenyl)-5-hydroxy-hepta-1,4,6-trien-3-one

Suppliers and Price of Didemethyl Curcumin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Didemethyl Curcumin
50mg
$ 446.00

TRC
DidemethylCurcumin
10mg
$ 145.00

Biosynth Carbosynth
Didemethyl curcumin
50 mg
$ 700.00

Biosynth Carbosynth
Didemethyl curcumin
10 mg
$ 190.00

Biosynth Carbosynth
Didemethyl curcumin
5 mg
$ 100.00

Biosynth Carbosynth
Didemethyl curcumin
2 mg
$ 60.00

Biosynth Carbosynth
Didemethyl curcumin
25 mg
$ 425.00

AK Scientific
DidemethylCurcumin
10mg
$ 306.00

Total 5 raw suppliers

Chemical Property of Didemethyl Curcumin

Chemical Property:

Melting Point:202-206°C (dec.)
PSA：115.06000
LogP:2.76390
Storage Temp.:-20?C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:340.09468823
Heavy Atom Count:25
Complexity:480

Purity/Quality:

99% ^*data from raw suppliers

Didemethyl Curcumin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)O)O)O
Isomeric SMILES:C1=CC(=C(C=C1/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O

Technology Process of Didemethyl Curcumin

There total 16 articles about Didemethyl Curcumin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 458-37-7
curcumin

: 60831-46-1
bisdemethylcurcumin

Guidance literature:: With boron tribromide; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2018.08.084

Reference yield: 60.0%

: 458-37-7
curcumin

: 149732-51-4
1-(4-hydroxy-3-methoxyphenyl)-7-(3,4-dihydroxyphenyl)-1,6-heptadiene-3,5-dione

: 60831-46-1
bisdemethylcurcumin

Guidance literature:: With pyridine; aluminium trichloride; In dichloromethane; for 24h; Heating;
DOI:10.1021/jm970190x

Reference yield: 51.0%

: 123-54-6,81235-32-7
acetylacetone

: 139-85-5
3,4-dihydroxybenzaldehyde

: 60831-46-1
bisdemethylcurcumin

Guidance literature:: acetylacetone; With boron trioxide; In ethyl acetate; at 40 ℃; for 0.5h;

3,4-dihydroxybenzaldehyde; With boric acid tributyl ester; In ethyl acetate; for 0.5h;

With N-butylamine; In ethyl acetate; at 40 ℃; for 4.5h;
DOI:10.1016/j.foodchem.2009.09.024