Isopropyltriphenylphosphonium bromide

Base Information

• Chemical Name: Isopropyltriphenylphosphonium bromide
• CAS No.: 1530-33-2
• Molecular Formula: C21H22 P . Br
• Molecular Weight: 385.283
• Hs Code.: 2931599090
• European Community (EC) Number: 625-444-8
• NSC Number: 113130
• DSSTox Substance ID: DTXSID50383613
• Mol file: 1530-33-2.mol

Synonyms:Isopropyltriphenylphosphonium bromide;1530-33-2;Isopropyl(triphenyl)phosphonium bromide;triphenyl(propan-2-yl)phosphanium;bromide;2-Propyltriphenylphosphonium Bromide;Isopropyl(triphenyl]phosphonium bromide;Isopropyl-triphenyl-phosphonium iodide;Isopropyl(triphenyl)phosphoniumbromide;SCHEMBL1010505;DTXSID50383613;HSOZCYIMJQTYEX-UHFFFAOYSA-M;Isopropyltriphenylphosphoniumbromide;Triphenylisopropylphosphonium bromide;MFCD00064807;NSC113130;AKOS000280724;NSC-113130;Phosphonium, isopropyltriphenyl-, bromide;FT-0674116;F17171;Phosphonium, (1-methylethyl)triphenyl-, bromide;A883854

Chemical Property of Isopropyltriphenylphosphonium bromide

Chemical Property:

• Melting Point: 239-240 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 13.59000
• Density: g/cm³
• LogP: 1.39290
• Solubility.: Methanol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 384.06425
• Heavy Atom Count: 23
• Complexity: 271

Purity/Quality:

98%, ^*data from raw suppliers

2-Propyltriphenylphosphonium Bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C)[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]
• Uses: Shows antiviral activity.

Technology Process of Isopropyltriphenylphosphonium bromide

There total 1 articles about Isopropyltriphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

triphenylphosphine (603-35-0) + isopropyl bromide (75-26-3) → isopropyltriphenylphosphonium bromide (1530-33-2)

Guidance literature:

at 150 ℃; for 23h; under 9000.9 Torr; Autoclave;

DOI:10.1002/chem.201203005

Reference yield: 90.0%

isopropyltriphenylphosphonium bromide (1530-33-2) + methyl 4-formylbenzoate (1571-08-0) → methyl 4-(2-methylprop-1-en-1-yl)benzoate (115665-61-7)

Guidance literature:

With potassium carbonate; In 1,4-dioxane; at 110 ℃; for 10h;

DOI:10.1016/j.tet.2021.132535

Reference yield: 88.0%

1-(4-tolylsulfonyl)indole-3-carboxaldehyde (50562-79-3) + isopropyltriphenylphosphonium bromide (1530-33-2) → 3-(2-methylprop-1-en-1-yl)-1-(phenylsulfonyl)-1H-indole

Guidance literature:

isopropyltriphenylphosphonium bromide; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 2h;

1-(4-tolylsulfonyl)indole-3-carboxaldehyde; In tetrahydrofuran; at -78 - 20 ℃; for 5h;

DOI:10.1039/c9ob02520k

upstream raw materials:

triphenylphosphine

isopropyl bromide

Downstream raw materials:

(4-methylpent-3-en-1-yn-1-yl)benzene

methyl 3-methyl-2-phenylbut-2-enoate

3-Methyl-2-p-tolyl-but-2-enoic acid methyl ester

2-(2-Chloro-phenyl)-3-methyl-but-2-enoic acid methyl ester

Refernces

• 1、 Gassman,P.G. et al.. "-". . p. 7741 - 7748. Retrieved 1972.
• 2、 Moore, Peter W.,Read, Christopher D. G.,Bernhardt, Paul V.,Williams, Craig M.. "ATP3 and MTP3: Easily Prepared Stable Perruthenate Salts for Oxidation Applications in Synthesis". supporting information. p. 4556 - 4561. Retrieved 2018/03/13.