2-Bromopropane

Base Information

• Chemical Name: 2-Bromopropane
• CAS No.: 75-26-3
• Molecular Formula: C3H7Br
• Molecular Weight: 122.993
• Hs Code.: 2930909090
• European Community (EC) Number: 200-855-1
• UN Number: 2344
• UNII: R651XOV97Z
• DSSTox Substance ID: DTXSID7030197
• Nikkaji Number: J1.447H
• Wikipedia: 2-Bromopropane
• Wikidata: Q209323
• ChEMBL ID: CHEMBL451810
• Mol file: 75-26-3.mol

Synonyms:2-bromopropane;isopropyl bromide

Chemical Property of 2-Bromopropane

Chemical Property:

• Appearance/Colour: Colorless transparent liquid
• Vapor Pressure: 205mmHg at 25°C
• Melting Point: -89 °C
• Refractive Index: n20/D 1.425(lit.)
• Boiling Point: 60.6 °C at 760 mmHg
• Flash Point: 19.4 °C
• PSA: 0.00000
• Density: 1.342 g/cm³
• LogP: 1.78970
• Water Solubility.: 0.3 g/100 mL
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 121.97311
• Heavy Atom Count: 4
• Complexity: 10.8

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F,T
• Hazard Codes: F:Flammable;;
• Statements: R11:; R48/20:; R60:; R66:
• Safety Statements: S16:; S45:; S53:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Brominated Solvents
• Canonical SMILES: CC(C)Br

Technology Process of 2-Bromopropane

There total 88 articles about 2-Bromopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.8%

propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) → propyl bromide (106-94-5) + isopropyl bromide (75-26-3)

Guidance literature:

With hydrogen bromide; oxygen; at 20 - 23 ℃; for 4.5h; under 1551.49 - 1603.2 Torr;

Reference yield: 96.0%

propane (74-98-6) → isopropyl bromide (75-26-3)

Guidance literature:

With 2AlBr₃*CBr₄; bromine; at -20 ℃; for 3h;

DOI:10.1016/0040-4039(95)01986-R

Reference yield: 93.0%

isopropyl alcohol (67-63-0,8013-70-5) → isopropyl bromide (75-26-3)

Guidance literature:

With carbon tetrabromide; sodium bromide; In N,N-dimethyl-formamide; for 3h; Catalytic behavior; Irradiation;

DOI:10.1039/c5cc03067f

upstream raw materials:

2-iodo-propane

propene

1,2-Dibromopropane

propane

Downstream raw materials:

1-(1-methylethyl)piperazine

2-isopropyl-2H-indazole

2-isopropylmercapto-4-methyl-quinoline

4-isopropylamino-1,2-dimethyl-5-phenyl-1,2-dihydro-pyrazol-3-one

Refernces

• 1、 Hayashi, Yoshihito,Inada, Yasuhiro,Katayama, Misaki,Kikukawa, Yuji,Kitajima, Hiromasa,Seto, Kensuke,Watanabe, Daiki,Yamashita, Shohei. "Induced Fitting and Polarization of a Bromine Molecule in an Electrophilic Inorganic Molecular Cavity and Its Bromination Reactivity". supporting information. p. 14399 - 14403. Retrieved 2020/07/13.
• 2、 -. "METHODS AND COMPOSITIONS FOR TREATING HIV-RELATED DISORDERS". Paragraph 0213. . Retrieved 2016/02/10.