2-Iodo-4,5-dimethoxybenzaldehyde

Base Information

• Chemical Name: 2-Iodo-4,5-dimethoxybenzaldehyde
• CAS No.: 61203-53-0
• Molecular Formula: C9H9IO3
• Molecular Weight: 292.073
• DSSTox Substance ID: DTXSID90451880
• Nikkaji Number: J1.804.668G
• Wikidata: Q82272163
• Mol file: 61203-53-0.mol

Synonyms:2-Iodo-4,5-dimethoxybenzaldehyde;61203-53-0;MFCD13193552;SCHEMBL1589608;DTXSID90451880;SPKQIKMTTNYPHW-UHFFFAOYSA-N;AKOS016015244;CS-0365087

Chemical Property of 2-Iodo-4,5-dimethoxybenzaldehyde

Chemical Property:

• Vapor Pressure: 2.75E-05mmHg at 25°C
• Boiling Point: 357.3oC at 760 mmHg
• Flash Point: 169.9oC
• PSA: 35.53000
• Density: 1.706g/cm3
• LogP: 2.12090
• Storage Temp.: 2-8°C
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 291.95964
• Heavy Atom Count: 13
• Complexity: 174

Purity/Quality:

99% ^*data from raw suppliers

2-Iodo-4,5-dimethoxybenzaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C(=C1)C=O)I)OC

Technology Process of 2-Iodo-4,5-dimethoxybenzaldehyde

There total 14 articles about 2-Iodo-4,5-dimethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,4-dimethoxy-benzaldehyde (120-14-9) → 2-iodo-4,5-dimethoxybenzaldehyde (61203-53-0)

Guidance literature:

With N-iodo-succinimide; trifluoroacetic acid; In acetonitrile; for 6h; Reflux;

DOI:10.3390/molecules181215613

Reference yield: 95.0%

2-bromomethyl-1-iodo-4,5-dimethoxybenzene (110451-87-1) → 2-iodo-4,5-dimethoxybenzaldehyde (61203-53-0)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; for 1008h; Ambient temperature;

Reference yield:

2-bromo-4,5-dimethoxybenzaldehyde dimethyl acetal (70461-33-5) → 2-iodo-4,5-dimethoxybenzaldehyde (61203-53-0)

Guidance literature:

With n-butyllithium; iodine; acetic acid; In tetrahydrofuran; ethyl acetate;

upstream raw materials:

2-amino-4,5-dimethoxybenzaldehyde

3,4-dimethoxy-benzaldehyde

2-(2-bromo-4,5-dimethoxyphenyl)-1,3-dioxolane

2-bromomethyl-1-iodo-4,5-dimethoxybenzene

Downstream raw materials:

[1-(2-Iodo-4,5-dimethoxy-phenyl)-meth-(E)-ylidene]-trimethylsilanyl-amine

2-bromomethyl-1-iodo-4,5-dimethoxybenzene

4,5-dimethoxy-2-iodo-N-methylbenzylamine

N-benzyl-2-iodo-4,5-dimethoxybenzylamine