2-[3-(Dimethylamino)propyl]-2-(3-methoxyphenyl)cyclopentan-1-one

Base Information

Chemical Name:2-[3-(Dimethylamino)propyl]-2-(3-methoxyphenyl)cyclopentan-1-one
CAS No.:61321-35-5
Molecular Formula:C₁₇H₂₅NO₂
Molecular Weight:275.391
Hs Code.:
DSSTox Substance ID:DTXSID10510887

Synonyms:61321-35-5;2-[3-(Dimethylamino)propyl]-2-(3-methoxyphenyl)cyclopentan-1-one;SCHEMBL11636640;DTXSID10510887

Suppliers and Price of 2-[3-(Dimethylamino)propyl]-2-(3-methoxyphenyl)cyclopentan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[3-(Dimethylamino)propyl]-2-(3-methoxyphenyl)cyclopentan-1-one

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:275.188529040
Heavy Atom Count:20
Complexity:329

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)CCCC1(CCCC1=O)C2=CC(=CC=C2)OC

Technology Process of 2-[3-(Dimethylamino)propyl]-2-(3-methoxyphenyl)cyclopentan-1-one

There total 4 articles about 2-[3-(Dimethylamino)propyl]-2-(3-methoxyphenyl)cyclopentan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36282-40-3
(3-methoxyphenyl)magnesium bromide

: 61321-35-5
2-(3-Dimethylaminopropyl)-2-(3-methoxyphenyl)cyclopentanon

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / 30percent H₂SO₄ / diethyl ether / 1 h / Heating

2: 38 percent / 85percent HCOOH, 30percent H₂O₂ / Ambient temperature

3: 1.) NaNH₂ / 1.) benzene, reflux, 1 h, 2.) benzene, reflux, overnight

With formic acid; sulfuric acid; dihydrogen peroxide; sodium amide; In diethyl ether;
DOI:10.1021/jm00354a016

Reference yield:

: 36742-36-6
1-(3-methoxyphenyl)cyclopentene

: 61321-35-5
2-(3-Dimethylaminopropyl)-2-(3-methoxyphenyl)cyclopentanon

Guidance literature:: Multi-step reaction with 2 steps

1: 38 percent / 85percent HCOOH, 30percent H₂O₂ / Ambient temperature

2: 1.) NaNH₂ / 1.) benzene, reflux, 1 h, 2.) benzene, reflux, overnight

With formic acid; dihydrogen peroxide; sodium amide;
DOI:10.1021/jm00354a016

Reference yield:

: 31503-28-3
(±)-2-(3-methoxyphenyl)cyclopentan-1-one

: 109-54-6
3-(Dimethylamino)propyl chloride

: 61321-35-5
2-(3-Dimethylaminopropyl)-2-(3-methoxyphenyl)cyclopentanon

Guidance literature:: With sodium amide; Yield given. Multistep reaction; 1.) benzene, reflux, 1 h, 2.) benzene, reflux, overnight;
DOI:10.1021/jm00354a016