Methyl 3-(1-benzyl-1H-indol-3-yl)prop-2-enoate

Base Information

Chemical Name:Methyl 3-(1-benzyl-1H-indol-3-yl)prop-2-enoate
CAS No.:61364-29-2
Molecular Formula:C19H17NO2
Molecular Weight:291.349
Hs Code.:
DSSTox Substance ID:DTXSID30708941

Synonyms:61364-29-2;Methyl 3-(1-benzyl-1H-indol-3-yl)prop-2-enoate;SCHEMBL9054395;DTXSID30708941

Suppliers and Price of Methyl 3-(1-benzyl-1H-indol-3-yl)prop-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 3-(1-benzyl-1H-indol-3-yl)prop-2-enoate

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:291.125928785
Heavy Atom Count:22
Complexity:400

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C=CC1=CN(C2=CC=CC=C21)CC3=CC=CC=C3

Technology Process of Methyl 3-(1-benzyl-1H-indol-3-yl)prop-2-enoate

There total 2 articles about Methyl 3-(1-benzyl-1H-indol-3-yl)prop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 3377-71-7
N-benzylindole

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 61364-29-2
3-(1-benzyl-1H-indol-3-yl)acrylic acid methyl ester

Guidance literature:: With copper diacetate; In dimethyl sulfoxide; N,N-dimethyl-formamide; at 130 ℃; for 12h; regioselective reaction; Inert atmosphere;
DOI:10.3762/bjoc.16.16

Reference yield:

: 5927-18-4
trimethyl phosphonoacetate

: 10511-51-0
1-Benzylindole-3-carboxaldehyde

: 61364-29-2
3-(1-benzyl-1H-indol-3-yl)acrylic acid methyl ester

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 0 ℃;

Reference yield: 90.0%

: 61364-29-2
3-(1-benzyl-1H-indol-3-yl)acrylic acid methyl ester

: 682-30-4
Diethyl vinylphosphonate

: 1073968-33-8
methyl 9-benzyl-9H-carbazole-3-carboxylate

Guidance literature:: With dipotassium peroxodisulfate; silver(I) acetate; palladium diacetate; at 130 ℃; for 24h; regioselective reaction; Sealed tube;
DOI:10.1021/acs.orglett.5b02265