Phenylphosphoramidic dichloride

Base Information

• Chemical Name: Phenylphosphoramidic dichloride
• CAS No.: 6955-57-3
• Molecular Formula: C6H6 Cl2 N O P
• Molecular Weight: 210
• NSC Number: 67643
• DSSTox Substance ID: DTXSID20290244
• Nikkaji Number: J893.210G
• Wikidata: Q82027863
• Mol file: 6955-57-3.mol

Synonyms:phenylphosphoramidic dichloride;6955-57-3;N-dichlorophosphorylaniline;Phosphoramidic dichloride, phenyl-;NSC67643;N-phenylamidodichlorophosphate;DTXSID20290244;NSC-67643

Chemical Property of Phenylphosphoramidic dichloride

Chemical Property:

• Vapor Pressure: 0.00328mmHg at 25°C
• Boiling Point: 282.8°Cat760mmHg
• Flash Point: 124.8°C
• Density: 1.507g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 208.9564062
• Heavy Atom Count: 11
• Complexity: 164

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NP(=O)(Cl)Cl

Technology Process of Phenylphosphoramidic dichloride

There total 6 articles about Phenylphosphoramidic dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

aniline (62-53-3) → phenylamidophosphoric dichloride (6955-57-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate; In 5,5-dimethyl-1,3-cyclohexadiene; at 90 ℃; for 0.5h;

DOI:10.1021/acs.joc.9b00377

Reference yield: 60.0%

aniline hydrochloride (142-04-1,36663-09-9) → phenylamidophosphoric dichloride (6955-57-3)

Guidance literature:

With trichlorophosphate; at 120 - 140 ℃; for 5h;

Reference yield:

rac-methylbenzylamine (618-36-0) → phenylamidophosphoric dichloride (6955-57-3)

Guidance literature:

upstream raw materials:

aniline hydrochloride

aniline

rac-methylbenzylamine

trichlorophosphate

Downstream raw materials:

N-Phenyl-N',N''-diethylenetriamide of phosphoric acid

(2-oxo-2,3-dihydro-1H-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-phenyl-amine

phenyl-amidophosphoric acid diphenyl ester

trans-2-N-phenylamino-2-oxo-4-methyl-1,3,2-dioxaphosphorinane