Ethyl 3-anilino-2-cyano-3-methylsulfanylprop-2-enoate

Base Information

Chemical Name:Ethyl 3-anilino-2-cyano-3-methylsulfanylprop-2-enoate
CAS No.:61485-25-4
Molecular Formula:C13H14N2O2S
Molecular Weight:262.332
Hs Code.:
DSSTox Substance ID:DTXSID60400769
Mol file:61485-25-4.mol

Synonyms:61485-25-4;ethyl 2-cyano-3-(methylsulfanyl)-3-(phenylamino)prop-2-enoate;ethyl 3-anilino-2-cyano-3-methylsulfanylprop-2-enoate;MS-6201;ethyl (Z)-3-anilino-2-cyano-3-(methylsulfanyl)-2-propenoate;DTXSID60400769;SXJJUZCQEIWUAO-UHFFFAOYSA-N;AKOS005110509;ethyl 2-cyano-3-methylthio-3-phenylaminoacrylate;ethyl 3-phenylamino-3-methylthio-2-cyanoacrylate;(Z)-ethyl 2-cyano-3-(methylthio)-3-(phenylamino)acrylate

Suppliers and Price of Ethyl 3-anilino-2-cyano-3-methylsulfanylprop-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethyl 3-anilino-2-cyano-3-methylsulfanylprop-2-enoate

Chemical Property:

PSA：87.42000
LogP:2.83278
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:262.07759887
Heavy Atom Count:18
Complexity:364

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=C(NC1=CC=CC=C1)SC)C#N

Technology Process of Ethyl 3-anilino-2-cyano-3-methylsulfanylprop-2-enoate

There total 6 articles about Ethyl 3-anilino-2-cyano-3-methylsulfanylprop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 17823-58-4
ethyl 2-cyano-3,3-di(methylsulfanyl)acrylate

: 62-53-3
aniline

: 61485-25-4
ethyl 3-anilino-3-(methylthio)acrylonitrile-2-carboxylate

Guidance literature:: In ethanol; for 10h; Heating;

Reference yield: 63.0%

: 103-72-0
phenyl isothiocyanate

: 105-56-6
ethyl 2-cyanoacetate

: 74-88-4
methyl iodide

: 61485-25-4
ethyl 3-anilino-3-(methylthio)acrylonitrile-2-carboxylate

Guidance literature:: ethyl 2-cyanoacetate; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h; Sealed tube;

phenyl isothiocyanate; In N,N-dimethyl-formamide; at 0 - 20 ℃; Sealed tube;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Sealed tube;
DOI:10.1039/d1ob01151k