5-Chloro-4-dimethylamino-2-methoxybenzoic acid

Base Information

Chemical Name:5-Chloro-4-dimethylamino-2-methoxybenzoic acid
CAS No.:61695-09-8
Molecular Formula:C10H12ClNO3
Molecular Weight:229.663
Hs Code.:
DSSTox Substance ID:DTXSID20454329
Wikidata:Q82275793

Synonyms:5-chloro-4-dimethylamino-2-methoxybenzoic acid;61695-09-8;SCHEMBL3655431;DTXSID20454329;KZKOWXZFTMYRSE-UHFFFAOYSA-N;AKOS018252846

Suppliers and Price of 5-Chloro-4-dimethylamino-2-methoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-Chloro-4-dimethylamino-2-methoxybenzoic acid

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:229.0505709
Heavy Atom Count:15
Complexity:235

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=C(C=C(C(=C1)OC)C(=O)O)Cl

Technology Process of 5-Chloro-4-dimethylamino-2-methoxybenzoic acid

There total 1 articles about 5-Chloro-4-dimethylamino-2-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 7206-70-4
4-amino-5-chloro-2-methoxybenzoic acid

: 61695-09-8
5-chloro-4-dimethylamino-2-methoxybenzoic acid

Guidance literature:: With sodium cyanoborohydride; In water; acetonitrile; at 20 ℃;
DOI:10.1248/cpb.50.941

Reference yield: 88.0%

: 61695-09-8
5-chloro-4-dimethylamino-2-methoxybenzoic acid

: 110859-47-7,140646-11-3
(4-benzylmorpholin-2-yl)methanamine

: 112885-55-9
N-<(4-benzyl-2-morpholinyl)methyl>-5-chloro-4-(dimethylamino)-2-methoxybenzamide

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 4h; Ambient temperature;
DOI:10.1021/jm00167a020

Reference yield:

: 61695-09-8
5-chloro-4-dimethylamino-2-methoxybenzoic acid

: 1154414-78-4
C₁₀H₁₃ClN₂O₂

Guidance literature:: 5-chloro-4-dimethylamino-2-methoxybenzoic acid; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

With ammonia; In 1,4-dioxane; N,N-dimethyl-formamide; at -10 - 20 ℃; for 0.5h; ice-ethanol bath;