(1)Benzothieno(2,3-d)pyrimidin-4-one, 5,6,7,8-tetrahydro-3-(4-fluorophenyl)-2-methyl-

Base Information

Chemical Name:(1)Benzothieno(2,3-d)pyrimidin-4-one, 5,6,7,8-tetrahydro-3-(4-fluorophenyl)-2-methyl-
CAS No.:34387-08-1
Molecular Formula:C17H15FN2OS
Molecular Weight:314.3772
Hs Code.:
DSSTox Substance ID:DTXSID70187958
Nikkaji Number:J41.941I
Wikidata:Q83059714
Mol file:34387-08-1.mol

Synonyms:BRN 0561562;34387-08-1;(1)Benzothieno(2,3-d)pyrimidin-4-one, 5,6,7,8-tetrahydro-3-(4-fluorophenyl)-2-methyl-;3-(p-Fluorophenyl)-2-methyl-4-oxo-5,6-tetramethylenethieno(2,3-d)pyrimidine;C17H15FN2OS;DTXSID70187958;LS-41032;3-(4-Fluorophenyl)-5,6,7,8-tetrahydro-2-methyl[1]benzothieno[2,3-d]pyrimidin-4(3H)-one;[1]Benzothieno[2,3-d]pyrimidin-4(3H)-one, 3-(4-fluorophenyl)-5,6,7,8-tetrahydro-2-methyl-;[1]Benzothieno[2,3-d]pyrimidin-4(3H)-one, 3-(p-fluorophenyl)-5,6,7,8-tetrahydro-2-methyl-

Suppliers and Price of (1)Benzothieno(2,3-d)pyrimidin-4-one, 5,6,7,8-tetrahydro-3-(4-fluorophenyl)-2-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1)Benzothieno(2,3-d)pyrimidin-4-one, 5,6,7,8-tetrahydro-3-(4-fluorophenyl)-2-methyl-

Chemical Property:

Vapor Pressure:9.1E-11mmHg at 25°C
Boiling Point:516.3°Cat760mmHg
Flash Point:266.1°C
PSA：63.13000
Density:1.41g/cm³
LogP:3.77350
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:314.08891244
Heavy Atom Count:22
Complexity:489

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(C3=C(S2)CCCC3)C(=O)N1C4=CC=C(C=C4)F

Technology Process of (1)Benzothieno(2,3-d)pyrimidin-4-one, 5,6,7,8-tetrahydro-3-(4-fluorophenyl)-2-methyl-

There total 3 articles about (1)Benzothieno(2,3-d)pyrimidin-4-one, 5,6,7,8-tetrahydro-3-(4-fluorophenyl)-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

: 13130-47-7
2-Methyl-5,6,7,8-tetrahydro-4H-<1>benzothieno<2,3-d><1,3>oxazin-4-on

: 371-40-4
4-fluoroaniline

: 34387-08-1
3-(4-fluoro-phenyl)-2-methyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one

Guidance literature:: at 160 - 170 ℃;

Reference yield:

: 5936-58-3
2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid

: 34387-08-1
3-(4-fluoro-phenyl)-2-methyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: Heating

DOI:10.1021/jm00271a034

Reference yield:

: 13130-43-3
2-acetamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid

: 34387-08-1
3-(4-fluoro-phenyl)-2-methyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / acetic anhydride / 1 h / Heating

2: 21 percent / 160 - 170 °C

With acetic anhydride;