[(2,2-Difluoroethenyl)oxy]benzene

Base Information

• Chemical Name: [(2,2-Difluoroethenyl)oxy]benzene
• CAS No.: 61698-69-9
• Molecular Formula: C8H6F2O
• Molecular Weight: 156.132
• DSSTox Substance ID: DTXSID10495125
• Nikkaji Number: J973.668I
• Mol file: 61698-69-9.mol

Synonyms:[(2,2-Difluoroethenyl)oxy]benzene;61698-69-9;SCHEMBL9011498;DTXSID10495125;AUODECJMVGZWOY-UHFFFAOYSA-N

Chemical Property of [(2,2-Difluoroethenyl)oxy]benzene

Chemical Property:

• PSA: 9.23000
• LogP: 2.80330
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 156.03867113
• Heavy Atom Count: 11
• Complexity: 135

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC=C(F)F

Technology Process of [(2,2-Difluoroethenyl)oxy]benzene

There total 4 articles about [(2,2-Difluoroethenyl)oxy]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

polytetrafluoroethylene (116-14-3,82785-14-6) + vinyl phenyl ether (766-94-9) → 2,2-Difluorovinyl-phenylaether (61698-69-9)

Guidance literature:

With RuCl₂(1,3-dimesityl-4,5,6,7-tetrahydro-1,3-diazepin-2-ylidene)(=CH-2-(2-PrO)C₆H₄); In ethyl acetate; at 60 ℃; for 9h; under 1520.1 Torr; Reagent/catalyst; Solvent; Inert atmosphere;

DOI:10.1021/jacs.1c10574

Reference yield:

polytetrafluoroethylene (116-14-3,82785-14-6) + vinyl phenyl ether (766-94-9) → Vinylidene fluoride (75-38-7) + 2,2-Difluorovinyl-phenylaether (61698-69-9) + trans 1,2-dibenzoylethylene (73421-43-9) + 1,2-cis-diphenoxyethylene (73421-47-3)

Guidance literature:

With C₃₄H₄₀Cl₂N₂O₃Ru; In toluene; at 60 ℃; for 4h; under 760.051 Torr; Reagent/catalyst; Solvent; Pressure; Inert atmosphere;

DOI:10.1021/jacs.1c10574

Reference yield:

polytetrafluoroethylene (116-14-3,82785-14-6) + vinyl phenyl ether (766-94-9) → 2,2-Difluorovinyl-phenylaether (61698-69-9) + 1,2-diphenoxy-ethene (266304-28-3)

Guidance literature:

With Hoveyda-Grubbs catalyst second generation; In 1,2-dichloro-ethane; at 60 ℃; for 4h; under 760.051 Torr; Reagent/catalyst; Solvent; Inert atmosphere;

DOI:10.1021/jacs.1c10574

upstream raw materials:

polytetrafluoroethylene

vinyl phenyl ether

Downstream raw materials:

3,3-difluoro-2-phenoxy-1-tert-butylthio-1-cyanocyclobutane

trans 1,2-dibenzoylethylene

1,2-cis-diphenoxyethylene