1,3,5-Trimethyl-N-phenyl-1H-pyrazole-4-carboxamide

Base Information

Chemical Name:1,3,5-Trimethyl-N-phenyl-1H-pyrazole-4-carboxamide
CAS No.:61747-84-0
Molecular Formula:C₁₃H₁₅N₃O
Molecular Weight:229.282
Hs Code.:
DSSTox Substance ID:DTXSID30598243
Nikkaji Number:J2.524.723J
Wikidata:Q82493976

Synonyms:61747-84-0;1,3,5-Trimethyl-N-phenyl-1H-pyrazole-4-carboxamide;1,3,5-TRIMETHYL-N-PHENYLPYRAZOLE-4-CARBOXAMIDE;DTXSID30598243;AKOS009126964;N-phenyl-1,3,5-trimethylpyrazole-4-carboxamide;Z241918940

Suppliers and Price of 1,3,5-Trimethyl-N-phenyl-1H-pyrazole-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,3,5-Trimethyl-N-phenyl-1H-pyrazole-4-carboxamide

Chemical Property:

PSA：50.41000
LogP:2.67320
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:229.121512110
Heavy Atom Count:17
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=NN1C)C)C(=O)NC2=CC=CC=C2

Technology Process of 1,3,5-Trimethyl-N-phenyl-1H-pyrazole-4-carboxamide

There total 5 articles about 1,3,5-Trimethyl-N-phenyl-1H-pyrazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 260047-11-8
3,5-dimethyl-4-(N-phenylcarbamoyl)isoxazole

: 61747-84-0
N-Phenyl-1,3,5-trimethylpyrazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Raney nickel / methanol / 3 h / 760.05 Torr

2: 85 mg / methanol / 12 h / Heating

With hydrogen; nickel; In methanol;
DOI:10.1016/j.tet.2007.09.046

Reference yield:

: 2510-36-3
3,5-dimethyl-4-isoxazolecarboxylic acid

: 61747-84-0
N-Phenyl-1,3,5-trimethylpyrazole-4-carboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: oxalyl chloride; DMF / CH₂Cl₂

2: triethylamine / CH₂Cl₂

3: H₂ / Raney nickel / methanol / 3 h / 760.05 Torr

4: 85 mg / methanol / 12 h / Heating

With oxalyl dichloride; hydrogen; triethylamine; N,N-dimethyl-formamide; nickel; In methanol; dichloromethane;
DOI:10.1016/j.tet.2007.09.046

Reference yield:

: 31301-45-8
3,5-dimethylisoxazole-4-carbonyl chloride

: 61747-84-0
N-Phenyl-1,3,5-trimethylpyrazole-4-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / CH₂Cl₂

2: H₂ / Raney nickel / methanol / 3 h / 760.05 Torr

3: 85 mg / methanol / 12 h / Heating

With hydrogen; triethylamine; nickel; In methanol; dichloromethane;
DOI:10.1016/j.tet.2007.09.046