(5-Methoxy-2-methylphenyl)boronic acid

Base Information

Chemical Name:(5-Methoxy-2-methylphenyl)boronic acid
CAS No.:617689-07-3
Molecular Formula:C8H11BO3
Molecular Weight:165.985
Hs Code.:2931900090
DSSTox Substance ID:DTXSID40590733
Wikidata:Q82484374
Mol file:617689-07-3.mol

Synonyms:617689-07-3;(5-Methoxy-2-methylphenyl)boronic acid;5-Methoxy-2-methylphenylboronic acid;5-Methoxy-2-methyl benzeneboronic acid;MFCD03425973;(5-methoxy-2-methyl-phenyl)boronic acid;Boronic acid, (5-methoxy-2-methylphenyl)-;(5-Methoxy-2-methylphenyl)boronicacid;5-Methoxy-2-Methylphenyl Boronic acid;SCHEMBL1960037;DTXSID40590733;QUQJFILPCCJEGB-UHFFFAOYSA-N;AMY29973;5-methoxy-2-methyl-phenylboronic acid;AKOS006280039;AB14734;CS-W018771;DS-14889;SY102829;DB-344775;O10130;EN300-1301028;A868640

Suppliers and Price of (5-Methoxy-2-methylphenyl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(5-Methoxy-2-methylphenyl)boronicAcid
500mg
$ 285.00

Matrix Scientific
(5-Methoxy-2-methylphenyl)boronic acid 95+%
1g
$ 864.00

Matrix Scientific
(5-Methoxy-2-methylphenyl)boronic acid 95+%
250mg
$ 346.00

Crysdot
(5-Methoxy-2-methylphenyl)boronicacid 97%
1g
$ 339.00

Chemcia Scientific
5-Methoxy-2-methylphenylboronicacid
0.5 G
$ 265.00

AOBChem
5-Methoxy-2-Methylphenylboronicacid 97%
10g
$ 1160.00

AOBChem
5-Methoxy-2-Methylphenylboronicacid 97%
500mg
$ 136.00

American Custom Chemicals Corporation
5-METHOXY-2-METHYLBENZENEBORONIC ACID 95.00%
1G
$ 698.25

American Custom Chemicals Corporation
5-METHOXY-2-METHYLBENZENEBORONIC ACID 95.00%
5MG
$ 505.95

Alichem
5-Methoxy-2-methylphenylboronicacid
1g
$ 1701.85

Total 31 raw suppliers

Chemical Property of (5-Methoxy-2-methylphenyl)boronic acid

Chemical Property:

Boiling Point:334.9±52.0 °C(Predicted)
PKA:8.18±0.58(Predicted)
PSA：49.69000
Density:1.14±0.1 g/cm3(Predicted)
LogP:-0.31660
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:166.0801244
Heavy Atom Count:12
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

(5-Methoxy-2-methylphenyl)boronicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B(C1=C(C=CC(=C1)OC)C)(O)O
Uses (5-Methoxy-2-methylphenyl)boronic Acid is used in preparation of Phenyl-substituted Imidazopyridine Amides useful in the treatment of cardiovascular and other disorders.

Technology Process of (5-Methoxy-2-methylphenyl)boronic acid

There total 4 articles about (5-Methoxy-2-methylphenyl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 36942-56-0
3-bromo-4-methylanisole

: 617689-07-3
(5-methoxy-2-methylphenyl)boronic acid

Guidance literature:: 3-bromo-4-methylanisole; With magnesium; ethylene dibromide; In tetrahydrofuran; at 50 ℃; for 1h;

Trimethyl borate; In tetrahydrofuran; at 0 - 25 ℃; for 1.25h;
DOI:10.1002/anie.201801130

Reference yield: 69.0%

: 36942-56-0
3-bromo-4-methylanisole

: 617689-07-3
(5-methoxy-2-methylphenyl)boronic acid

Guidance literature:: 3-bromo-4-methylanisole; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.333333h;

With Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 2h;

With hydrogenchloride; water; In tetrahydrofuran;

Reference yield:

: 60710-39-6
3-bromo-p-cresol

: 617689-07-3
(5-methoxy-2-methylphenyl)boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide / dichloromethane / 2 h / 25 °C

2.1: magnesium; ethylene dibromide / tetrahydrofuran / 1 h / 50 °C

2.2: 1.25 h / 0 - 25 °C

With N-benzyl-N,N,N-triethylammonium chloride; magnesium; ethylene dibromide; sodium hydroxide; In tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.201801130