N-Pyrazinylthiourea

Base Information

• Chemical Name: N-Pyrazinylthiourea
• CAS No.: 31437-05-5
• Molecular Formula: C5H6 N4 S
• Molecular Weight: 154.195
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID60185362
• Mol file: 31437-05-5.mol

Synonyms:N-pyrazinylthiourea

Chemical Property of N-Pyrazinylthiourea

Chemical Property:

• Vapor Pressure: 0.000557mmHg at 25°C
• Melting Point: 128 °C
• Boiling Point: 311.6°Cat760mmHg
• PKA: 11.25±0.70(Predicted)
• Flash Point: 142.3°C
• PSA: 95.92000
• Density: 1.482g/cm³
• LogP: 0.90540
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 154.03131738
• Heavy Atom Count: 10
• Complexity: 127

Purity/Quality:

97% ^*data from raw suppliers

pyrazin-2-ylthiourea ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(C=N1)NC(=S)N

Technology Process of N-Pyrazinylthiourea

There total 7 articles about N-Pyrazinylthiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-benzoyl-3-pyrazin-2-yl-thiourea (31437-04-4) → 1-(pyrazin-2-yl)thiourea (31437-05-5)

Guidance literature:

With sodium hydroxide; In water; at 80 ℃; for 0.333333h;

Reference yield: 64.0%

→ 1-(pyrazin-2-yl)thiourea (31437-05-5)

Guidance literature:

In ethanol; at 20 ℃;

Reference yield: 49.0%

ethyl[(pyrazin-2-ylamino)carbonothioyl]carbamate (56406-73-6) → 1-(pyrazin-2-yl)thiourea (31437-05-5)

Guidance literature:

With sodium hydroxide; for 3h; Heating;

upstream raw materials:

2-Aminopyrazine

potassium thioacyanate

ethyl[(pyrazin-2-ylamino)carbonothioyl]carbamate

1-benzoyl-3-pyrazin-2-yl-thiourea

Downstream raw materials:

N-(pyrazin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine

3-[5-Bromo-2-(pyrazin-2-ylamino)-thiazol-4-yl]-benzonitrile