Ethanone, 1-(2-amino-5-bromophenyl)-2-chloro-

Base Information

Chemical Name:Ethanone, 1-(2-amino-5-bromophenyl)-2-chloro-
CAS No.:61871-82-7
Molecular Formula:C8H7BrClNO
Molecular Weight:248.507
Hs Code.:
DSSTox Substance ID:DTXSID80443471
Wikidata:Q82261318

Synonyms:61871-82-7;Ethanone, 1-(2-amino-5-bromophenyl)-2-chloro-;SCHEMBL8398733;DTXSID80443471;2'-Amino-5'-bromo-2-chloroacetophenone

Suppliers and Price of Ethanone, 1-(2-amino-5-bromophenyl)-2-chloro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethanone, 1-(2-amino-5-bromophenyl)-2-chloro-

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:246.93995
Heavy Atom Count:12
Complexity:176

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Br)C(=O)CCl)N

Technology Process of Ethanone, 1-(2-amino-5-bromophenyl)-2-chloro-

There total 4 articles about Ethanone, 1-(2-amino-5-bromophenyl)-2-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 107-14-2
chloroacetonitrile

: 106-40-1
4-bromo-aniline

: 61871-82-7
1-(2-amino-5-bromophenyl)-2-chloroethan-1-one

Guidance literature:: With aluminium trichloride; boron trichloride; Yield given. Multistep reaction; 1.) dichloromethane, benzene, 5 - 10 deg C, 2.) dichloromethane, benzene, reflux, 20 h;
DOI:10.1016/S0223-5234(96)80002-X

Reference yield:

: 106-40-1
4-bromo-aniline

: 61871-82-7
1-(2-amino-5-bromophenyl)-2-chloroethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: boron trichloride / dichloromethane / 3 h / 0 °C / Inert atmosphere

1.2: 6 h / 0 °C / Reflux; Inert atmosphere

2.1: hydrogenchloride; water / dichloromethane / Reflux; Inert atmosphere

With hydrogenchloride; water; boron trichloride; In dichloromethane;
DOI:10.1002/adsc.201701028