Technology Process of Diethyl [(4-aminophenyl)methyl]propanedioate
There total 6 articles about Diethyl [(4-aminophenyl)methyl]propanedioate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
methanol;
for 3h;
under 1500.15 Torr;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) NaH / 1.) DMF, 30 min, room temperature, 2.a) DMF, 30 min, room temperature, b.) 2 h, 90 deg C
2: 9.2 g / H2 / 10percent Pd-C / ethyl acetate / 4 h / Ambient temperature
With
hydrogen; sodium hydride;
palladium on activated charcoal;
In
ethyl acetate;
DOI:10.1248/cpb.39.2323
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: NaH / dimethylsulfoxide / 15 °C
1.2: dimethylsulfoxide / 15 °C
2.1: H2 / Pd/C / ethanol / atmospheric pressure
With
hydrogen; sodium hydride;
palladium on activated charcoal;
In
ethanol; dimethyl sulfoxide;
DOI:10.1021/jm0502541
