Ethyl 2-hydroxy-2-methyl-4-phenylbut-3-ynoate

Base Information

Chemical Name:Ethyl 2-hydroxy-2-methyl-4-phenylbut-3-ynoate
CAS No.:61922-14-3
Molecular Formula:C13H14O3
Molecular Weight:218.24800
Hs Code.:
DSSTox Substance ID:DTXSID30534146

Synonyms:Ethyl 2-hydroxy-2-methyl-4-phenylbut-3-ynoate;61922-14-3;SCHEMBL10729135;DTXSID30534146;AXBXBSDDLWWMRC-UHFFFAOYSA-N;ethyl-2-hydroxy-2-methyl-4-phenylbutynoate

Suppliers and Price of Ethyl 2-hydroxy-2-methyl-4-phenylbut-3-ynoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl 2-hydroxy-2-methyl-4-phenylbut-3-ynoate

Chemical Property:

PSA：46.53000
LogP:1.35220
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:218.094294304
Heavy Atom Count:16
Complexity:304

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)(C#CC1=CC=CC=C1)O

Technology Process of Ethyl 2-hydroxy-2-methyl-4-phenylbut-3-ynoate

There total 6 articles about Ethyl 2-hydroxy-2-methyl-4-phenylbut-3-ynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 617-35-6
2-oxo-propionic acid ethyl ester

: 536-74-3
phenylacetylene

: 61922-14-3
ethyl 2-hydroxy-2-methyl-4-phenyl-but-3-ynoate

Guidance literature:: phenylacetylene; With ethylmagnesium bromide; In diethyl ether; for 2h; Reflux; Inert atmosphere;

2-oxo-propionic acid ethyl ester; In diethyl ether; for 3.5h; Inert atmosphere; Reflux;
DOI:10.1002/hc.21096