(R)-3-Nonanol

Base Information

• Chemical Name: (R)-3-Nonanol
• CAS No.: 61925-50-6
• Molecular Formula: C₉H₂₀O
• Molecular Weight: 144.257
• UNII: 0V3924UKG7
• Nikkaji Number: J58.756G
• Wikidata: Q27237285
• Mol file: 61925-50-6.mol

Synonyms:(R)-3-Nonanol;3-Nonanol, (3R)-;3(R)-Nonanol;(-)-3-Nonanol;3-Nonanol, (R)-;(R)-(-)-3-Nonanol;61925-50-6;UNII-0V3924UKG7;0V3924UKG7;(3R)-3-nonanol;SCHEMBL13283545;Q27237285

Chemical Property of (R)-3-Nonanol

Chemical Property:

• PSA: 20.23000
• LogP: 2.72770
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 144.151415257
• Heavy Atom Count: 10
• Complexity: 61.7

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCC(CC)O
• Isomeric SMILES: CCCCCC[C@@H](CC)O

Technology Process of (R)-3-Nonanol

There total 14 articles about (R)-3-Nonanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

nonan-3-ol (185019-15-2) → (R)-3-nonanol (61925-50-6)

Guidance literature:

With alcohol dehydrogenase from Thermoanaerobium brockii; NADH-specific (R)-selective-ADH; YcnD-oxidoreductase; at 30 ℃; for 6h; pH=7.5; optical yield given as %ee; enantiospecific reaction; aq. buffer; Resolution of racemate; Enzymatic reaction;

DOI:10.1021/ja804816a

Reference yield: 90.0%

heptanal (111-71-7) + diethylzinc (557-20-0) → (R)-3-nonanol (61925-50-6)

Guidance literature:

With titanium(IV) isopropylate; chiral binaphthol based ligand; In dichloromethane; at -25 ℃; for 2h;

DOI:10.1021/ol0358511

Reference yield: 75.0%

heptanal (111-71-7) + diethylzinc (557-20-0) → (S)-nonan-3-ol (61925-49-3) + (R)-3-nonanol (61925-50-6)

Guidance literature:

(R,R)-6,6'-bis(2,2-dimethyl-1-hydroxypropyl)-2,2'-bipyridine; In hexane; toluene; at 0 ℃; for 3h; Yields of byproduct given. Title compound not separated from byproducts;

upstream raw materials:

heptanal

diethylzinc

n-hexylmagnesium bromide

propionaldehyde

Downstream raw materials:

(3S)-nonan-3-yl (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoate