185019-15-2Relevant articles and documents
Stereospecific internal almylation of terminal γ,δ-epoxy acrylates
Miyazawa, Masahiro,Ishibashi, Naoki,Ohnuma, Satoshi,Miyashita, Masaaki
, p. 3419 - 3422 (1997)
The alkylation of ethyl (S)- and (R)-4,5-epoxy-2-pentenoates (11) and (12), chiral terminal γ,δ-epoxy acrylates prepared from D-mannitol, by trialkylaluminum in the presence of water occurs rcgioselectively at the γ position, i.e., at the internal position, to yield a sole product respectively with net inversion of configuration. The method provides useful chiral synthons for natural product synthesis.
ALKANE OXIDATION BY MODIFIED HYDROXYLASES
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Paragraph 0323; 0324, (2016/02/16)
This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable substrate with such cells.
Titanocene-catalyzed regiodivergent epoxide openings
Gansaeuer, Andreas,Fan, Chun-An,Keller, Florian,Keil, Jutta
, p. 3484 - 3485 (2008/01/01)
The first regiodivergent opening of unbiased epoxides providing the ring-opened products in high enantiomeric excess from racemic and exceptionally high enantiomeric excess from enantioenriched substrates in a double asymmetric process has been devised. It constitutes a more general case of the very important enantioselective openings of meso-epoxides. Copyright