Methyl 4-hydrazinylbenzoate Hydrochloride

Base Information

• Chemical Name: Methyl 4-hydrazinylbenzoate Hydrochloride
• CAS No.: 6296-89-5
• Molecular Formula: C8H10 N2 O2 . Cl H
• Molecular Weight: 202.641
• European Community (EC) Number: 827-941-7
• NSC Number: 17185
• Mol file: 6296-89-5.mol

Synonyms:6296-89-5;Methyl 4-hydrazinylbenzoate Hydrochloride;methyl 4-hydrazinobenzoate hydrochloride;Methyl 4-hydrazinylbenzoate HCl;4-hydrazinobenzoic acid methyl ester hydrochloride;methyl 4-hydrazinylbenzoate;hydrochloride;MFCD01325154;4-(Carbomethoxy)phenylhydrazine;SCHEMBL1192202;MXSGRGCOQOKOEH-UHFFFAOYSA-N;4-(Methoxycarbonyl)phenylhydrazine;NSC17185;AB9723;NSC-17185;AKOS002390526;Methyl4-hydrazinylbenzoateHydrochloride;SB77487;Methyl-4-hydrazinylbenzoate hydrochloride;AS-18973;methyl 4-hydrazineylbenzoate hydrochloride;SY038219;CS-0132197;FT-0707141;EN300-1271980;2-(4-(methoxycarbonyl)phenyl)hydrazinium chloride;A868292;4-hydrazino-benzoic acid methyl ester hydrochloride

Chemical Property of Methyl 4-hydrazinylbenzoate Hydrochloride

Chemical Property:

• Vapor Pressure: 0.000357mmHg at 25°C
• Melting Point: 205-207 °C
• Boiling Point: 318.6°C at 760 mmHg
• Flash Point: 146.5°C
• PSA: 64.35000
• Density: 1.24g/cm³
• LogP: 2.33410
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 202.0509053
• Heavy Atom Count: 13
• Complexity: 153

Purity/Quality:

97% ^*data from raw suppliers

Methyl4-hydrazinylbenzoatehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CC=C(C=C1)NN.Cl
• Uses: Methyl 4-hydrazinylbenzoate HCl

Technology Process of Methyl 4-hydrazinylbenzoate Hydrochloride

There total 3 articles about Methyl 4-hydrazinylbenzoate Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-hydrazino-benzoic acid (5326-27-2) → [4-(methoxycarbonyl)phenyl]hydrazine hydrochloride (6296-89-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; at 90 ℃; for 5h; Product distribution / selectivity;

Reference yield: 80.0%

methanol (67-56-1) + 4-hydrazinobenzoic acid hydrochloride (24589-77-3,52455-33-1) → [4-(methoxycarbonyl)phenyl]hydrazine hydrochloride (6296-89-5)

Guidance literature:

With hydrogenchloride; In water; at 65 - 70 ℃; for 4h; Inert atmosphere;

DOI:10.1021/op5001463

Reference yield:

4-methoxycarbonyl aniline (619-45-4) → [4-(methoxycarbonyl)phenyl]hydrazine hydrochloride (6296-89-5)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; sodium nitrite; In water; at 0 - 5 ℃; for 0.75h; Inert atmosphere;

DOI:10.1002/anie.201306098

upstream raw materials:

2-hydrazino-benzoic acid

4-methoxycarbonyl aniline

methanol

4-hydrazinobenzoic acid hydrochloride

Downstream raw materials:

methyl 4-[4-(2-Adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoate

methyl 4-[4-(2-adamantylcarbamoyl)-5-(1-methylcyclopropyl)pyrazol-1-yl]benzoate

methyl 4-[4-(2-adamantylcarbamoyl)-5-cyclopentylpyrazol-1-yl]benzoate

tert-butyl 5-amino-1-(4-methoxycarbonylphenyl)pyrazole-4-carboxylate