2,6-Bis(benzyloxy)aniline

Base Information

Chemical Name:2,6-Bis(benzyloxy)aniline
CAS No.:61999-92-6
Molecular Formula:C20H19NO2
Molecular Weight:305.376
Hs Code.:
DSSTox Substance ID:DTXSID90509436
Wikidata:Q82367009

Synonyms:2,6-bis(benzyloxy)aniline;Benzenamine, 2,6-bis(phenylmethoxy)-;61999-92-6;SCHEMBL11828242;DTXSID90509436;GBCLSWYQELUKHR-UHFFFAOYSA-N

Suppliers and Price of 2,6-Bis(benzyloxy)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,6-Bis(benzyloxy)aniline

Chemical Property:

PSA：44.48000
LogP:5.00800
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:305.141578849
Heavy Atom Count:23
Complexity:294

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=C(C(=CC=C2)OCC3=CC=CC=C3)N

Technology Process of 2,6-Bis(benzyloxy)aniline

There total 4 articles about 2,6-Bis(benzyloxy)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 2-(2,6-dihydroxyphenyl)isoindoline-1,3-dione

: 100-39-0
benzyl bromide

: 61999-92-6
2,6-di(benzyloxy)aniline

Guidance literature:: 2-(2,6-dihydroxyphenyl)isoindoline-1,3-dione; benzyl bromide; With hydrogen; potassium carbonate; In acetone; at 20 ℃; under 3800.26 Torr; Reflux;

With hydrazine hydrate; In ethanol; at 95 ℃; Sealed tube;
DOI:10.1002/chem.201803575

Reference yield:

: 62000-10-6
(((2-nitro-1,3-phenylene)bis(oxy))bis(methylene))dibenzene

: 61999-92-6
2,6-di(benzyloxy)aniline

Guidance literature:: With ammonium chloride; zinc; In water; acetone; at 20 ℃;
DOI:10.1039/d0cc04590j

Reference yield:

: 601-89-8
2-nitroresorcinol

: 61999-92-6
2,6-di(benzyloxy)aniline

Guidance literature:: Multi-step reaction with 3 steps

1.1: palladium 10% on activated carbon; hydrogen / ethanol / 24 h / 20 °C / 3800.26 Torr / Sealed tube

2.1: potassium carbonate / 0.67 h / 160 °C / Inert atmosphere

3.1: hydrogen; potassium carbonate / acetone / 20 °C / 3800.26 Torr / Reflux

3.2: 95 °C / Sealed tube

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In ethanol; acetone; 3.2: |Balz-Schiemann Reaction;
DOI:10.1002/chem.201803575