methyl 2-methylbutyl ether

Base Information

• Chemical Name: methyl 2-methylbutyl ether
• CAS No.: 62016-48-2
• Molecular Formula: C6H14O
• Molecular Weight: 102.17500
• Hs Code.: 2909199090
• Mol file: 62016-48-2.mol

Synonyms:Methyl-(2-methyl-butyl)-aether;1-methoxy-2-methyl-butane;Butane,1-methoxy-2-methyl;Butane, 1-methoxy-2-methyl-;METHYL 2-METHYLBUTYL ETHER;

Chemical Property of methyl 2-methylbutyl ether

Chemical Property:

• Melting Point: -105.78°C (estimate)
• Refractive Index: 1.3820
• Boiling Point: 91.54°C (estimate)
• PSA: 9.23000
• Density: 0.7460
• LogP: 1.67890

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-methylbutyl ether

There total 2 articles about methyl 2-methylbutyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(+/-)-2-methyl-1-butanol (137-32-6) + methyl iodide (74-88-4) → 1-methoxy-2-methyl-butane (62016-48-2)

Guidance literature:

With sodium hydride; 1-n-butyl-2,3-dimethylimidazolium hexafluorophosphate; at 25 ℃; for 2h;

DOI:10.1080/00304940409355387

Reference yield: 68.0%

trimethyl phosphite (512-56-1) + (+/-)-2-methyl-1-butanol (137-32-6) → 1-methoxy-2-methyl-butane (62016-48-2)

Guidance literature:

With PPA; at 180 - 190 ℃; for 4h;

DOI:10.3891/acta.chem.scand.52-1223

Reference yield:

1-methoxy-2-methyl-butane (62016-48-2) → C19H23NO7S

Guidance literature:

Multi-step reaction with 2 steps

1.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C

1.2: 20 °C

2.1: caesium carbonate / acetonitrile / 100 °C

With di-isopropyl azodicarboxylate; caesium carbonate; triphenylphosphine; In tetrahydrofuran; acetonitrile;

upstream raw materials:

(+/-)-2-methyl-1-butanol

methyl iodide

trimethyl phosphite

Refernces

• 1、 Van Dyke Tiers, George. "Direct methylation of primary and secondary alcohols by trimethyl phosphate to prepare pure alkyl methyl ethers". . p. 1223 - 1233. Retrieved 2007/10/03.