2-(2-Phenylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Base Information

Chemical Name:2-(2-Phenylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
CAS No.:6208-44-2
Molecular Formula:C19H20N2
Molecular Weight:276.381
Hs Code.:
NSC Number:665300
DSSTox Substance ID:DTXSID20327544
Wikidata:Q82089419
ChEMBL ID:CHEMBL1971548

Synonyms:NSC665300;2-(2-Phenylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole;6208-44-2;Oprea1_641311;2-phenethyl-1,3,4,5-tetrahydropyrido[4,3-b]indole;CHEMBL1971548;DTXSID20327544;NSC-665300;NCI60_022511

Suppliers and Price of 2-(2-Phenylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(2-Phenylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:276.162648646
Heavy Atom Count:21
Complexity:337

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC2=C1NC3=CC=CC=C23)CCC4=CC=CC=C4

Technology Process of 2-(2-Phenylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

There total 2 articles about 2-(2-Phenylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1346446-53-4
(3-chlorophenyl)-(1-phenethylpiperidin-4-ylidene)amine

: 6208-44-2
2-(2-phenylethyl)-1,2,3,4-tetrahydropyrido<4,3-b>indole

Guidance literature:: With sodium amide; sodium t-butanolate; In tetrahydrofuran; at 55 - 60 ℃; for 24h; Inert atmosphere;

Reference yield:

: 39742-60-4
1-(2-phenylethyl)-4-piperidinone

: 108-42-9
3-chloro-aniline

: 6208-44-2
2-(2-phenylethyl)-1,2,3,4-tetrahydropyrido<4,3-b>indole

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / toluene / Reflux

2: sodium amide; sodium t-butanolate / tetrahydrofuran / 24 h / 60 °C / Inert atmosphere; Green chemistry

With toluene-4-sulfonic acid; sodium amide; sodium t-butanolate; In tetrahydrofuran; toluene;
DOI:10.1002/jhet.2150