2-Hydroxy-2-methyl-N-(4-nitrophenyl)propanamide

Base Information

Chemical Name:2-Hydroxy-2-methyl-N-(4-nitrophenyl)propanamide
CAS No.:62100-54-3
Molecular Formula:C10H12N2O4
Molecular Weight:224.216
Hs Code.:2924299090
ChEMBL ID:CHEMBL403513
DSSTox Substance ID:DTXSID00488647
Wikidata:Q82331444
Mol file:62100-54-3.mol

Synonyms:62100-54-3;2-Hydroxy-2-methyl-N-(4-nitrophenyl)propanamide;CHEMBL403513;SCHEMBL8410636;DTXSID00488647

Suppliers and Price of 2-Hydroxy-2-methyl-N-(4-nitrophenyl)propanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Hydroxy-2-methyl-N-(4-nitrophenyl)propanamide

Chemical Property:

Melting Point:178-180 °C(Solv: ethanol (64-17-5))
Boiling Point:457.5±30.0 °C(Predicted)
PKA:13.17±0.29(Predicted)
PSA：95.15000
Density:1.359±0.06 g/cm3(Predicted)
LogP:1.90040
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:224.07970687
Heavy Atom Count:16
Complexity:277

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])O

Technology Process of 2-Hydroxy-2-methyl-N-(4-nitrophenyl)propanamide

There total 4 articles about 2-Hydroxy-2-methyl-N-(4-nitrophenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62100-49-6
2-(4-Nitrophenyloxy)-2-methylpropionsaeureamid

: 62100-54-3
2-hydroxy-4'-nitroisobutyranilide

Guidance literature:: Multistep reaction; (i) NaH, dioxane, (ii) H₂O;
DOI:10.1055/s-1977-24262

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 62100-54-3
2-hydroxy-4'-nitroisobutyranilide

Guidance literature:: Multi-step reaction with 3 steps

1: (i) NaOH, (ii) /BRN= 1731042/

2: (i) SOCl₂, (ii) NH₃, dioxane

3: (i) NaH, dioxane, (ii) H₂O

DOI:10.1055/s-1977-24262

Reference yield:

: 17431-97-9
2-(4-nitrophenoxy)-2-methylpropanoic acid

: 62100-54-3
2-hydroxy-4'-nitroisobutyranilide

Guidance literature:: Multi-step reaction with 2 steps

1: (i) SOCl₂, (ii) NH₃, dioxane

2: (i) NaH, dioxane, (ii) H₂O

DOI:10.1055/s-1977-24262