2-Hydroxy-N,2-dimethyl-N-(4-nitrophenyl)propanamide

Base Information

Chemical Name:2-Hydroxy-N,2-dimethyl-N-(4-nitrophenyl)propanamide
CAS No.:62100-57-6
Molecular Formula:C₁₁H₁₄N₂O₄
Molecular Weight:238.243
Hs Code.:
DSSTox Substance ID:DTXSID10488658
Wikidata:Q82331460

Synonyms:2-Hydroxy-N,2-dimethyl-N-(4-nitrophenyl)propanamide;62100-57-6;DTXSID10488658

Suppliers and Price of 2-Hydroxy-N,2-dimethyl-N-(4-nitrophenyl)propanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 2-Hydroxy-N,2-dimethyl-N-(4-nitrophenyl)propanamide

Chemical Property:

Melting Point:128-129 °C
Boiling Point:402.0±30.0 °C(Predicted)
PSA：86.36000
Density:1.298±0.06 g/cm3(Predicted)
LogP:1.85170
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:238.09535693
Heavy Atom Count:17
Complexity:303

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C(=O)N(C)C1=CC=C(C=C1)[N+](=O)[O-])O

Technology Process of 2-Hydroxy-N,2-dimethyl-N-(4-nitrophenyl)propanamide

There total 2 articles about 2-Hydroxy-N,2-dimethyl-N-(4-nitrophenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62100-50-9
2,N-Dimethyl-2-(4-nitro-phenoxy)-propionamide

: 62100-57-6
2-Hydroxy-2,N-dimethyl-N-(4-nitro-phenyl)-propionamide

Guidance literature:: Multistep reaction; (i) NaH, dioxane, (ii) H₂O;
DOI:10.1055/s-1977-24262

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 62100-57-6
2-Hydroxy-2,N-dimethyl-N-(4-nitro-phenyl)-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: (i) NaOH, (ii) /BRN= 1731042/

2: (i) SOCl₂, (ii) /BRN= 741851/, dioxane

3: (i) NaH, dioxane, (ii) H₂O

DOI:10.1055/s-1977-24262