2-Nitro-5-piperidinophenol

Base Information

Chemical Name:2-Nitro-5-piperidinophenol
CAS No.:157831-75-9
Molecular Formula:C11H14 N2 O3
Molecular Weight:222.244
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50379056
Wikidata:Q82168720
Mol file:157831-75-9.mol

Synonyms:157831-75-9;2-nitro-5-piperidinophenol;2-nitro-5-(piperidin-1-yl)phenol;2-nitro-5-piperidin-1-ylphenol;Phenol, 2-nitro-5-(1-piperidinyl)-;2-Nitro-5-(1-piperidinyl)phenol;Maybridge1_001384;Phenol,2-nitro-5-(1-piperidinyl)-;Oprea1_033675;SCHEMBL21066338;HMS545G20;DTXSID50379056;MFCD00052663;AKOS024318910;AS-62022;CS-0447580;FT-0613169

Suppliers and Price of 2-Nitro-5-piperidinophenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-NITRO-5-PIPERIDINOPHENOL 95.00%
25G
$ 1639.64

Alfa Aesar
2-Nitro-5-(1-piperidinyl)phenol, 97%
25g
$ 218.00

Alfa Aesar
2-Nitro-5-(1-piperidinyl)phenol, 97%
5g
$ 56.80

Alfa Aesar
2-Nitro-5-(1-piperidinyl)phenol, 97%
1g
$ 18.70

Total 7 raw suppliers

Chemical Property of 2-Nitro-5-piperidinophenol

Chemical Property:

Vapor Pressure:6.87E-07mmHg at 25°C
Melting Point:68-70°C
Boiling Point:397.6°Cat760mmHg
Flash Point:194.2°C
PSA：69.29000
Density:1.292g/cm³
LogP:2.87890
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:222.10044231
Heavy Atom Count:16
Complexity:248

Purity/Quality:

99% ^*data from raw suppliers

2-NITRO-5-PIPERIDINOPHENOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C2=CC(=C(C=C2)[N+](=O)[O-])O

Technology Process of 2-Nitro-5-piperidinophenol

There total 2 articles about 2-Nitro-5-piperidinophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 110-89-4
piperidine

: 446-36-6
5-fluoro-2-nitrophenol

: 157831-75-9
2-nitro-5-(piperidin-1'-yl)phenol

Guidance literature:: In acetonitrile; for 2h; Inert atmosphere; Reflux;
DOI:10.1016/j.bmcl.2014.05.088

Reference yield: 58.0%

: 157831-75-9
2-nitro-5-(piperidin-1'-yl)phenol

Guidance literature:: In acetonitrile; at 100 ℃; for 3h; Sealed tube;

Reference yield: 80.0%

: 157831-75-9
2-nitro-5-(piperidin-1'-yl)phenol

: 109-61-5
propoxycarbonyl chloride

: propyl (2-hydroxy-4-(piperidin-1-yl)phenyl)carbamate

Guidance literature:: 2-nitro-5-(piperidin-1'-yl)phenol; With hydrogen; nickel; In tetrahydrofuran; for 5h; under 1034.32 - 2585.81 Torr;

propoxycarbonyl chloride; With sodium hydrogencarbonate; In water; for 2h; Inert atmosphere; Cooling with ice;
DOI:10.1016/j.tet.2021.132304