4-(4-Methoxyphenyl)butanoic acid methyl ester

Base Information

• Chemical Name: 4-(4-Methoxyphenyl)butanoic acid methyl ester
• CAS No.: 20637-08-5
• Molecular Formula: C12H16O3
• Molecular Weight: 208.257
• Hs Code.: 2918990090
• Mol file: 20637-08-5.mol

Synonyms:methyl 4-methoxyphenylbutanoate;Benzenebutanoic acid,4-methoxy-,methyl ester;4-p-Anisylbuttersaeuremethylester;

Chemical Property of 4-(4-Methoxyphenyl)butanoic acid methyl ester

Chemical Property:

• Vapor Pressure: 0.00092mmHg at 25°C
• Boiling Point: 303.6°Cat760mmHg
• Flash Point: 123.6°C
• PSA: 35.53000
• Density: 1.045g/cm³
• LogP: 2.19090
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

≥99.0% ^*data from raw suppliers

Methyl4-(4-methoxyphenyl)butanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(4-Methoxyphenyl)butanoic acid methyl ester

There total 23 articles about 4-(4-Methoxyphenyl)butanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 4-(4-Methoxyphenyl)butyric acid (4521-28-2) → 4-(4-methoxyphenyl)butyric acid methyl ester (20637-08-5)

Guidance literature:

sulfuric acid; for 3h; Heating / reflux;

Reference yield: 99.0%

4-(4-Methoxyphenyl)butyric acid (4521-28-2) → 4-(4-methoxyphenyl)butyric acid methyl ester (20637-08-5)

Guidance literature:

With sulfuric acid; In methanol;

Reference yield: 98.0%

methanol (67-56-1) + 1-(4,4-dichlorobut-3-en-1-yl)-4-methoxybenzene → 4-(4-methoxyphenyl)butyric acid methyl ester (20637-08-5)

Guidance literature:

With triethylsilane; cyclohexa-1,4-diene; oxygen; cobalt acetylacetonate; In nonane; at 24 ℃; under 760.051 Torr; Reagent/catalyst;

DOI:10.1021/acs.joc.6b01709

upstream raw materials:

diazomethane

4-(4-Methoxyphenyl)butyric acid

acrylic acid methyl ester

p-methoxybenzyl chloride

Downstream raw materials:

2-methyl-5-(4-methoxyphenyl)-2-pentanol

4-<4-Methoxy-phenyl>-buttersaeure-hydrazid

2-hydroxy-4-(4-methoxy-phenyl)-butyric acid methyl ester

Refernces

• 1、 Miller,Gutierrez. "". . p. 1569. Retrieved 1978.
• 2、 Luo, Siyi,Peng, Marie,Querard, Pierre,Li, Chen-Chen,Li, Chao-Jun. "Copper-Catalyzed Conjugate Addition of Carbonyls as Carbanion Equivalent via Hydrazones". . p. 13111 - 13117. Retrieved 2021/09/18.