2-Thiophenecarboxamide, N-3-pyridinyl-

Base Information

Chemical Name:2-Thiophenecarboxamide, N-3-pyridinyl-
CAS No.:62289-81-0
Molecular Formula:C₁₀H₈N₂OS
Molecular Weight:204.252
Hs Code.:
DSSTox Substance ID:DTXSID80355060
Wikidata:Q82133672
Pharos Ligand ID:46RTJ2GSU3TR
ChEMBL ID:CHEMBL373784

Synonyms:62289-81-0;2-Thiophenecarboxamide, N-3-pyridinyl-;N-pyridin-3-ylthiophene-2-carboxamide;N-(pyridin-3-yl)thiophene-2-carboxamide;SW106065;SW-106065;SR-01000512777;SMR000069253;Oprea1_083771;Oprea1_245312;MLS000061185;CHEMBL373784;SCHEMBL6669304;DTXSID80355060;3-pyridyl thiophene-2-carboxamide;HMS1672C09;HMS2463O23;N-3-pyridinyl-2-thiophenecarboxamide;NSC755263;SPA03-091;STL377854;AKOS000626941;NSC-755263;SDCCGMLS-0043995.P002;NCGC00072088-02;MS-23107;HY-124778;CS-0087644;MLS000061185-02;MLS000061185-03;SR-01000512777-1;SR-01000512777-3;Z31791766

Suppliers and Price of 2-Thiophenecarboxamide, N-3-pyridinyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 2-Thiophenecarboxamide, N-3-pyridinyl-

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:204.03573406
Heavy Atom Count:14
Complexity:210

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CN=C1)NC(=O)C2=CC=CS2

Technology Process of 2-Thiophenecarboxamide, N-3-pyridinyl-

There total 4 articles about 2-Thiophenecarboxamide, N-3-pyridinyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 626-60-8
3-Chloropyridine

: 5813-89-8
2-thiophenylcarboxamide

: 62289-81-0
N-(pyridin-3-yl)thiophene-2-carboxamide

Guidance literature:: With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In tert-butyl alcohol; at 110 ℃; for 24h;
DOI:10.1021/ja0717414

Reference yield: 69.0%

: 1120-90-7
3-iodopyridine

: 5813-89-8
2-thiophenylcarboxamide

: 62289-81-0
N-(pyridin-3-yl)thiophene-2-carboxamide

Guidance literature:: With D-glucose; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane; copper(ll) bromide; sodium t-butanolate; In water; at 50 ℃; Inert atmosphere;
DOI:10.1002/chem.201700832

Reference yield:

: 527-72-0
2-thiophenylcarboxylic acid

: 62289-81-0
N-(pyridin-3-yl)thiophene-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / DMF / CH₂Cl₂ / 20 h / 20 °C

2: 230 mg / pyridine / CH₂Cl₂ / 3 h / 0 °C

With pyridine; thionyl chloride; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/jm061425k