4-Methyloxazole-5-carbonyl chloride

Base Information

Chemical Name:4-Methyloxazole-5-carbonyl chloride
CAS No.:62348-24-7
Molecular Formula:C5H4ClNO2
Molecular Weight:145.545
Hs Code.:2934999090
DSSTox Substance ID:DTXSID20383589
Nikkaji Number:J2.370.301G
Wikidata:Q82175369
Mol file:62348-24-7.mol

Synonyms:4-Methyloxazole-5-carbonyl chloride;62348-24-7;4-methyl-1,3-oxazole-5-carbonyl chloride;4-METHYLOXAZOLE-5-CARBONYLCHLORIDE;SCHEMBL891939;DTXSID20383589;YPKNOSGIABPXKS-UHFFFAOYSA-N;4-Methyl-5-oxazolecarbonyl chloride;MFCD06200856;4-methyl oxazole-5-carbonyl chloride;4-Methyl-oxazole-5-carbonyl chloride;4-methyl-oxazole-5-carbonyl-chloride;AKOS006344210;AT23456;AM101041;MS-22240;4-Methyloxazole-5-carboxylic acid chloride;FT-0692550;EN300-7088009;J-515796

Suppliers and Price of 4-Methyloxazole-5-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methyloxazole-5-carbonylchloride
50mg
$ 110.00

SynQuest Laboratories
4-Methyl-1,3-oxazole-5-carbonyl chloride 97%
250 mg
$ 176.00

SynQuest Laboratories
4-Methyl-1,3-oxazole-5-carbonyl chloride 97%
1 g
$ 424.00

Apolloscientific
4-Methyl-1,3-oxazole-5-carbonylchloride 97%
1g
$ 385.00

Apolloscientific
4-Methyl-1,3-oxazole-5-carbonylchloride 97%
250mg
$ 160.00

American Custom Chemicals Corporation
4-METHYLOXAZOLE-5-CARBONYL CHLORIDE 95.00%
250MG
$ 708.48

American Custom Chemicals Corporation
4-METHYLOXAZOLE-5-CARBONYL CHLORIDE 95.00%
1G
$ 894.76

AK Scientific
4-Methyloxazole-5-carbonylchloride
1g
$ 789.00

Total 7 raw suppliers

Chemical Property of 4-Methyloxazole-5-carbonyl chloride

Chemical Property:

Vapor Pressure:0.398mmHg at 25°C
Boiling Point:80oC
Flash Point:72.6oC
PSA：43.10000
Density:1.345g/cm3
LogP:1.36200
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:144.9930561
Heavy Atom Count:9
Complexity:128

Purity/Quality:

98%min ^*data from raw suppliers

4-Methyloxazole-5-carbonylchloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C
Statements: 14-34
Safety Statements: 22-26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(OC=N1)C(=O)Cl

Technology Process of 4-Methyloxazole-5-carbonyl chloride

There total 2 articles about 4-Methyloxazole-5-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 2510-32-9
4-methyl-1,3-oxazole-5-carboxylic acid

: 62348-24-7
4-Methyl-5-oxazolecarbonyl chloride

Guidance literature:: With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 9h;
DOI:10.1021/ol061697h

Reference yield:

: 20485-39-6
ethyl 4-methyloxazole-5-carboxylate

: 62348-24-7
4-Methyl-5-oxazolecarbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 6.04 g / aq. NaOH / 0.02 h / Heating

2: 94 percent / (COCl)2 / CH₂Cl₂; dimethylformamide / 9 h / 20 °C

With sodium hydroxide; oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol061697h

Reference yield: 78.0%

: 911297-40-0
2-(1-methyl-3-trimethylsilanyl-prop-2-ynyl)-phenylboronic acid

: 62348-24-7
4-Methyl-5-oxazolecarbonyl chloride

: 911297-36-4
(4-methyl-oxazol-5-yl)-[2-(1-methyl-3-trimethylsilanyl-prop-2-ynyl)-phenyl]methanone

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; In toluene; at 60 ℃; for 2h;
DOI:10.1021/ol061697h