4-Thiazolamine,2,5-dihydro-(9CI)

Base Information

• Chemical Name: 4-Thiazolamine,2,5-dihydro-(9CI)
• CAS No.: 623564-71-6
• Molecular Formula: C3H6N2S
• Molecular Weight: 102.15800
• Mol file: 623564-71-6.mol

Synonyms:4-thiazolamine,2,5-dihydro;

Chemical Property of 4-Thiazolamine,2,5-dihydro-(9CI)

Chemical Property:

• PSA: 61.18000
• LogP: 0.68610

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Thiazolamine,2,5-dihydro-(9CI)

There total 1 articles about 4-Thiazolamine,2,5-dihydro-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methylthio-2,5-dihydro-thiazole (623564-70-5) → thiazolidin-4-ylideneamine (623564-71-6)

Guidance literature:

With ammonium chloride; In ethanol; for 27.5h; Heating / reflux;

Reference yield: 15.0%

thiazolidin-4-ylideneamine (623564-71-6) + 2-bromo-3-(1-methylethoxy)-2-propenal (155272-73-4) → 7H-imidazo[1,2-c]thiazole-2-carbaldehyde (623564-72-7)

Guidance literature:

thiazolidin-4-ylideneamine; 2-bromo-3-(1-methylethoxy)-2-propenal; In acetonitrile; at 20 ℃; for 19.5h;

With triethylamine; In acetonitrile; for 2h; Heating / reflux;

Reference yield: 15.0%

thiazolidin-4-ylideneamine (623564-71-6) + 2-bromo-3-hydroxypropenal (19263-02-6) → 7H-imidazo[1,2-c]thiazole-2-carbaldehyde (623564-72-7)

Guidance literature:

thiazolidin-4-ylideneamine; 2-bromo-3-hydroxypropenal; In acetonitrile; at 20 ℃; for 19.5h;

With triethylamine; In acetonitrile; for 2h; Heating / reflux;

upstream raw materials:

4-methylthio-2,5-dihydro-thiazole

Downstream raw materials:

7H-imidazo[1,2-c]thiazole-2-carbaldehyde

Refernces

• 1、 -. "Process for preparing 6-alkylidene penem derivatives". . . Retrieved 2008/06/13.
• 2、 -. "PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES". Page/Page column 110. . Retrieved 2010/02/07.