5H,7H-Imidazo[1,2-c]thiazole-2-carboxaldehyde (9CI)

Base Information

• Chemical Name: 5H,7H-Imidazo[1,2-c]thiazole-2-carboxaldehyde (9CI)
• CAS No.: 623564-72-7
• Molecular Formula: C6H6N2OS
• Molecular Weight: 154.19000
• Mol file: 623564-72-7.mol

Synonyms:5H,7H-IMIDAZO[1,2-C]THIAZOLE-2-CARBOXALDEHYDE;5h,7h-imidazo[1,2-c]thiazole-2-carbaldehyde;7H-imidazo[1,2-c]thiazole-2-carbaldehyde;

Chemical Property of 5H,7H-Imidazo[1,2-c]thiazole-2-carboxaldehyde (9CI)

Chemical Property:

• Boiling Point: 436.3±35.0 °C(Predicted)
• PKA: 3.05±0.20(Predicted)
• PSA: 60.19000
• Density: 1.55±0.1 g/cm3(Predicted)
• LogP: 0.89990

Purity/Quality:

97% ^*data from raw suppliers

5H,7H-Imidazo[1,2-c]thiazole-2-carboxaldehyde 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5H,7H-Imidazo[1,2-c]thiazole-2-carboxaldehyde (9CI)

There total 3 articles about 5H,7H-Imidazo[1,2-c]thiazole-2-carboxaldehyde (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

thiazolidin-4-ylideneamine (623564-71-6) + 2-bromo-3-(1-methylethoxy)-2-propenal (155272-73-4) → 7H-imidazo[1,2-c]thiazole-2-carbaldehyde (623564-72-7)

Guidance literature:

thiazolidin-4-ylideneamine; 2-bromo-3-(1-methylethoxy)-2-propenal; In acetonitrile; at 20 ℃; for 19.5h;

With triethylamine; In acetonitrile; for 2h; Heating / reflux;

Reference yield: 15.0%

thiazolidin-4-ylideneamine (623564-71-6) + 2-bromo-3-hydroxypropenal (19263-02-6) → 7H-imidazo[1,2-c]thiazole-2-carbaldehyde (623564-72-7)

Guidance literature:

thiazolidin-4-ylideneamine; 2-bromo-3-hydroxypropenal; In acetonitrile; at 20 ℃; for 19.5h;

With triethylamine; In acetonitrile; for 2h; Heating / reflux;

Reference yield:

2-bromo-3-(1-methylethoxy)-2-propenal + thiazolidin-4-ylideneamine (623564-71-6) → 7H-imidazo[1,2-c]thiazole-2-carbaldehyde (623564-72-7)

Guidance literature:

With triethylamine; In dichloromethane; acetonitrile;

upstream raw materials:

thiazolidin-4-ylideneamine

2-bromo-3-(1-methylethoxy)-2-propenal

2-bromo-3-hydroxypropenal