4-(Ethoxymethyl)pyridine

Base Information

• Chemical Name: 4-(Ethoxymethyl)pyridine
• CAS No.: 62369-32-8
• Molecular Formula: C8H11NO
• Molecular Weight: 137.17900
• DSSTox Substance ID: DTXSID10487843
• Nikkaji Number: J3.515.478G
• Wikidata: Q82330123
• Mol file: 62369-32-8.mol

Synonyms:4-(Ethoxymethyl)pyridine;62369-32-8;Pyridine, 4-(ethoxymethyl)-;SCHEMBL9130156;DTXSID10487843

Chemical Property of 4-(Ethoxymethyl)pyridine

Chemical Property:

• PSA: 22.12000
• LogP: 1.61810
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 137.084063974
• Heavy Atom Count: 10
• Complexity: 79.3

Purity/Quality:

4-(Ethoxymethyl)pyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOCC1=CC=NC=C1

Technology Process of 4-(Ethoxymethyl)pyridine

There total 2 articles about 4-(Ethoxymethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium ethanolate (141-52-6) + 4-picolylchloride hydrochloride (1822-51-1) → 4-(ethoxymethyl)pyridine (62369-32-8)

Guidance literature:

With ethanol;

Reference yield:

sodium phenoxide (139-02-6) + 4-picolylchloride hydrochloride (1822-51-1) → 4-(ethoxymethyl)pyridine (62369-32-8) + 4-(phenoxymethyl)pyridine (63608-12-8)

Guidance literature:

With ethanol;

Reference yield: 85.0%

4-(ethoxymethyl)pyridine (62369-32-8) + 4-bromo-N,N-dimethylaniline (586-77-6) → C16H20N2O

Guidance literature:

With palladium diacetate; sodium hexamethyldisilazane; nixantphos; In 1,2-dimethoxyethane; at 23 ℃; chemoselective reaction;

DOI:10.1039/c5sc02739j

upstream raw materials:

sodium ethanolate

4-picolylchloride hydrochloride

sodium phenoxide

Downstream raw materials:

4-hydroxypropylpyridine