(3S)-3-Methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Base Information

Chemical Name:(3S)-3-Methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
CAS No.:62492-80-2
Molecular Formula:C16H14N2O
Molecular Weight:250.3
Hs Code.:
ChEMBL ID:CHEMBL396450
DSSTox Substance ID:DTXSID30489561

Synonyms:CHEMBL396450;62492-80-2;SCHEMBL3416882;DTXSID30489561;(3S)-3-Methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one;BDBM50233153

Suppliers and Price of (3S)-3-Methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3S)-3-Methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:250.110613074
Heavy Atom Count:19
Complexity:371

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C(=O)NC2=CC=CC=C2C(=N1)C3=CC=CC=C3
Isomeric SMILES:C[C@H]1C(=O)NC2=CC=CC=C2C(=N1)C3=CC=CC=C3

Technology Process of (3S)-3-Methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

There total 8 articles about (3S)-3-Methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 872873-91-1
S-[1-(2-benzoyl-phenylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester

: 62492-80-2
(S)-3-methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one

Guidance literature:: S-[1-(2-benzoyl-phenylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester; With hydrogenchloride; In chloroform; at 20 ℃;

With sodium hydrogencarbonate; In water;

With sodium hydroxide; In methanol; water; at 20 ℃; for 10h; pH=8.5;

Reference yield: 83.0%

aq sodium hydroxide: aq sodium hydroxide

: 1082051-52-2
tert-butyl 1-(2-benzoylphenylamino)-1-oxopropan-2-ylcarbamate

: 62492-80-2
(S)-3-methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one

Guidance literature:: With hydrogenchloride; benzophenone; sodium hydrogencarbonate; In chloroform; water; methanol hydrate;

Reference yield: 83.0%

: 1082051-52-2
tert-butyl 1-(2-benzoylphenylamino)-1-oxopropan-2-ylcarbamate

: 62492-80-2
(S)-3-methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one

Guidance literature:: With hydrogenchloride; sodium hydroxide; benzophenone; sodium hydrogencarbonate; In chloroform; water; methanol hydrate;