Technology Process of Benzenepropanamide,
N-(aminothioxomethyl)-a-chloro-4-(2-methyl-2-phenylpropoxy)-
There total 8 articles about Benzenepropanamide,
N-(aminothioxomethyl)-a-chloro-4-(2-methyl-2-phenylpropoxy)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / dimethyl sulfoxide
2: hydrogen / palladium on activated charcoal / methanol; benzene
3: (i) NaNO2, aq. HCl, acetone, (ii) /BRN= 635743/, CuCl
4: (i) SOCl2, (ii) /BRN= 605327/, Py, THF
With
hydrogen; sodium hydride;
palladium on activated charcoal;
In
methanol; dimethyl sulfoxide; benzene;
- Guidance literature:
-
With
pyridine; thiourea;
In
tetrahydrofuran; ethanol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 72 percent / NaH / dimethylsulfoxide / 3 h / 60 °C
2: H2 / 10percent Pd/C / benzene; ethanol / 760 Torr / Ambient temperature
3: 1.) 33percent NaNO2/H2O, conc. HCl, ethyl acrylate, 2.) Cu2O / 1.) acetone, ice cooling, 2.) 40 deg C, 2 h
4: 29.1 g / 25percent NaOH/H2O / methanol
5: 1.) SOCl2 / 1.) reflux, 2 h, 2.) THF, pyridine, ice bath, 40 min
With
copper(I) oxide; hydrogenchloride; sodium hydroxide; thionyl chloride; water; hydrogen; sodium hydride; ethyl acrylate; sodium nitrite;
palladium on activated charcoal;
In
methanol; ethanol; dimethyl sulfoxide; benzene;
