1-(2-Methyl-2-phenylpropoxy)-4-nitrobenzene

Base Information

Chemical Name:1-(2-Methyl-2-phenylpropoxy)-4-nitrobenzene
CAS No.:62517-29-7
Molecular Formula:C16H17NO3
Molecular Weight:271.316
Hs Code.:
DSSTox Substance ID:DTXSID40510810
Wikidata:Q82369321

Synonyms:1-(2-Methyl-2-phenylpropoxy)-4-nitrobenzene;62517-29-7;DTXSID40510810;SNUMJBFQBPXHEH-UHFFFAOYSA-N;4-(2,2-dimethyl-2-phenylethyloxy)nitrobenzene

Suppliers and Price of 1-(2-Methyl-2-phenylpropoxy)-4-nitrobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(2-Methyl-2-phenylpropoxy)-4-nitrobenzene

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:310

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(COC1=CC=C(C=C1)[N+](=O)[O-])C2=CC=CC=C2

Technology Process of 1-(2-Methyl-2-phenylpropoxy)-4-nitrobenzene

There total 1 articles about 1-(2-Methyl-2-phenylpropoxy)-4-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 2173-69-5
2-methyl-2-phenyl-propan-1-ol

: 100-00-5
4-chlorobenzonitrile

: 62517-29-7
4-(2-methyl-2-phenylpropyloxy)nitrobenzene

Guidance literature:: With sodium hydride; In dimethyl sulfoxide; at 60 ℃; for 3h;

Reference yield:

: 62517-29-7
4-(2-methyl-2-phenylpropyloxy)nitrobenzene

: 23234-43-7
D-tyrosine ethyl ester hydrochloride

Guidance literature:: Multi-step reaction with 8 steps

1: H₂ / 10percent Pd/C / benzene; ethanol / 760 Torr / Ambient temperature

2: 1.) 33percent NaNO₂/H₂O, conc. HCl, ethyl acrylate, 2.) Cu₂O / 1.) acetone, ice cooling, 2.) 40 deg C, 2 h

3: 29.1 g / 25percent NaOH/H₂O / methanol

5: 360 mg / 20percent HCl / 4 h / Ambient temperature

6: 220 mg / BBr₃ / CH₂Cl₂ / 0.33 h / Ambient temperature

7: 200 mg / NaN₃ / dimethylsulfoxide; H₂O / 3 h / 90 °C

8: 1.) H₂, 2.) HCl/Et₂O / 1.) 10percent Pd/C / 1.) ethanol, 1 atm, r.t.

With copper(I) oxide; hydrogenchloride; sodium hydroxide; sodium azide; diethyl ether; water; hydrogen; boron tribromide; ethyl acrylate; sodium nitrite; palladium on activated charcoal; In methanol; ethanol; dichloromethane; water; dimethyl sulfoxide; benzene;

Reference yield:

: 62517-29-7
4-(2-methyl-2-phenylpropyloxy)nitrobenzene

: 62517-30-0
4-(2-methyl-2-phenylpropyloxy)aniline

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr; Ambient temperature;
DOI:10.1248/cpb.30.3563