cis-6-Chloro-2-hexene

Base Information

• Chemical Name: cis-6-Chloro-2-hexene
• CAS No.: 62614-70-4
• Molecular Formula: C₆H₁₁Cl
• Molecular Weight: 118.606
• European Community (EC) Number: 679-920-5
• Wikidata: Q76422831
• Mol file: 62614-70-4.mol

Synonyms:cis-6-Chloro-2-hexene;62614-70-4;(Z)-6-chlorohex-2-ene;cis-4-Hexen-1-yl Chloride;SCHEMBL23925271;(2Z)-6-CHLOROHEX-2-ENE;MFCD02093458;AKOS006222801;C1653

Chemical Property of cis-6-Chloro-2-hexene

Chemical Property:

• Refractive Index: 1.4420-1.4450
• Boiling Point: 132oC
• PSA: 0.00000
• Density: 0.92
• LogP: 2.58150
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 118.0549280
• Heavy Atom Count: 7
• Complexity: 48.1

Purity/Quality:

98% ^*data from raw suppliers

cis-6-Chloro-2-hexene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC=CCCCCl
• Isomeric SMILES: C/C=C\CCCCl

Technology Process of cis-6-Chloro-2-hexene

There total 13 articles about cis-6-Chloro-2-hexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

6-chlorohex-2-yne (28077-73-8) → cis-1-chlorohex-4-ene (62614-72-6,68012-00-0,62614-70-4)

Guidance literature:

With hydrogen; Pd-BaSO₄; In pyridine; methanol;

DOI:10.1021/ja00079a033

Reference yield: 66.0%

hex-4-en-1-ol (6126-50-7,928-91-6,928-92-7) → cis-1-chlorohex-4-ene (62614-72-6,68012-00-0,62614-70-4)

Guidance literature:

With trichloroacetamide; triphenylphosphine; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/jacs.9b07489

Reference yield:

(E)-hex-4-en-1-ol (928-92-7) → trans-1-chlorohex-4-ene (62614-70-4,68012-00-0,62614-72-6)

Guidance literature:

With pyridine; thionyl chloride; chloroform;

DOI:10.1039/jr9570001788

upstream raw materials:

(E)-hex-4-en-1-ol

5-Hexen-1-ol

1,6-hexanediol

6-chlorohexene

Downstream raw materials:

2-ethylcyclopent-2-en-1-one

2-methyl-2-cyclohexen-1-one

4-propylbutanolide

3-<(E)-4-hexenyl>-2-cyclohexen-1-one

Refernces

• 1、 Sun, Shang-Zheng,Romano, Ciro,Martin, Ruben. "Site-selective catalytic deaminative alkylation of unactivated olefins". supporting information. p. 16197 - 16201. Retrieved 2019/10/17.
• 2、 Trost,Shi. "Diastereoselective cycloisomerizations of enediynes via palladium catalysis". . p. 12491 - 12509. Retrieved 2007/10/02.