2-ethyl-N-phenylhexanamide

Base Information

• Chemical Name: 2-ethyl-N-phenylhexanamide
• CAS No.: 62685-93-2
• Molecular Formula: C14H21NO
• Molecular Weight: 219.327
• Mol file: 62685-93-2.mol

Synonyms:Hexanamide,2-ethyl-N-phenyl;

Chemical Property of 2-ethyl-N-phenylhexanamide

Chemical Property:

• PSA: 32.59000
• LogP: 4.49100

Purity/Quality:

2-ETHYL-N-PHENYLHEXANAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ethyl-N-phenylhexanamide

There total 10 articles about 2-ethyl-N-phenylhexanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-Ethylhexanoic acid (149-57-5) + aniline (62-53-3) → 2-ethyl-N-phenylhexanamide (62685-93-2)

Guidance literature:

2-Ethylhexanoic acid; With iodine; triphenylphosphine; In acetonitrile; at 25 - 85 ℃; for 0.25h; Microwave irradiation; Green chemistry;

aniline; In acetonitrile; at 85 ℃; for 0.75h; chemoselective reaction; Microwave irradiation; Green chemistry;

DOI:10.1039/c6ra22558f

Reference yield: 85.0%

→ 2-ethyl-N-phenylhexanamide (62685-93-2)

Guidance literature:

With oxygen; In 1,2-dichloro-ethane; at 115 ℃; for 36h; Sealed tube;

Reference yield: 65.0%

2-ethyl-1-phenyl-hexan-1-one oxime → 2-ethyl-N-phenylhexanamide (62685-93-2) + N-(1-ethyl-pentyl)-benzamide (34021-58-4)

Guidance literature:

With trifluorormethanesulfonic acid; Tri(p-tolyl)phosphine; chloro(1,5-cyclooctadiene)rhodium(I) dimer; In 1,2-dichloro-ethane; for 3h; Heating;

DOI:10.1021/ol006951z

upstream raw materials:

methanol

2-Ethyl-2-trimethylsilanyl-hexanoic acid phenylamide

aniline

2-ethylhexanoyl fluoride