2-Bromo-4,6-dimethoxybenzoic acid

Base Information

Chemical Name:2-Bromo-4,6-dimethoxybenzoic acid
CAS No.:62827-49-0
Molecular Formula:C9H9BrO4
Molecular Weight:261.072
Hs Code.:
DSSTox Substance ID:DTXSID00479035
Nikkaji Number:J3.511.720B
Wikidata:Q82312888

Synonyms:2-Bromo-4,6-dimethoxybenzoic acid;62827-49-0;Benzoic acid, 2-bromo-4,6-dimethoxy-;DTXSID00479035;2-Bromo-4,6-dimethoxybenzoicacid;AMY28861;AKOS017549765;CS-0109609;D76885

Suppliers and Price of 2-Bromo-4,6-dimethoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Bromo-4,6-dimethoxybenzoic acid

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:259.96842
Heavy Atom Count:14
Complexity:209

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C(=C1)Br)C(=O)O)OC

Technology Process of 2-Bromo-4,6-dimethoxybenzoic acid

There total 4 articles about 2-Bromo-4,6-dimethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.4%

: 81574-69-8
2-bromo-4,6-dimethoxybenzaldehyde

: 62827-49-0
2-bromo-4,6-dimethoxybenzoic acid

Guidance literature:: With sodium chlorite; aminosulfonic acid; In tetrahydrofuran; water; at 25 ℃; for 1h; Reagent/catalyst;

Reference yield:

: 20469-65-2
1-bromo-3,5-dimethoxybenzene

: 62827-49-0
2-bromo-4,6-dimethoxybenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / 4.5 h / 0 - 100 °C / Inert atmosphere

2: sodium chlorite; sodium dihydrogenphosphate / tert-butyl alcohol; water / 0.25 h / 20 °C / Inert atmosphere

With sodium chlorite; sodium dihydrogenphosphate; trichlorophosphate; In water; tert-butyl alcohol; 1: |Vilsmeier-Haack Formylation;
DOI:10.1021/acs.joc.6b01503