Boc-trp-met-asp-phe-NH2

Base Information

Chemical Name:Boc-trp-met-asp-phe-NH2
CAS No.:5235-21-2
Molecular Formula:C34H44 N6 O8 S
Molecular Weight:696.825
Hs Code.:
European Community (EC) Number:226-032-7
ChEMBL ID:CHEMBL64605
Nikkaji Number:J297.948I
Mol file:5235-21-2.mol

Synonyms:Boc-CCK-4;Boc-CCK4;Boc-Trp-Met-Asp-Phe-NH2;butyloxycarbonyl-tryptophyl-methionyl-aspartyl-phenylalaninamide

Suppliers and Price of Boc-trp-met-asp-phe-NH2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BOC TETRAGASTRIN 95.00%
5MG
$ 498.03

Total 9 raw suppliers

Chemical Property of Boc-trp-met-asp-phe-NH2

Chemical Property:

Vapor Pressure:0.0268mmHg at 25°C
Boiling Point:255°C at 760 mmHg
Flash Point:108°C
PSA：247.11000
Density:1.097g/cm³
LogP:4.27780
XLogP3:2.3
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:19
Exact Mass:696.29413356
Heavy Atom Count:49
Complexity:1160

Purity/Quality:

99% ^*data from raw suppliers

BOC TETRAGASTRIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N

Technology Process of Boc-trp-met-asp-phe-NH2

There total 11 articles about Boc-trp-met-asp-phe-NH2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 5241-58-7
L-Phenylalanine amide

: 123197-15-9
Boc-Trp-Met-Asp-OH

: 5235-21-2
N-tert-butoxycarbonyl-L-tryptophyl->L-methionyl->L-α-aspartyl->L-phenylalanine amide

Guidance literature:: With thermolysin; In methanol; water; for 18h; Ambient temperature; pH 6.0;
DOI:10.1248/cpb.36.4345

Reference yield:

: 15160-31-3
(tert-butyloxycarbonyl)-l-tryptophan p-nitrophenyl ester

: 5235-21-2
N-tert-butoxycarbonyl-L-tryptophyl->L-methionyl->L-α-aspartyl->L-phenylalanine amide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 3 N HCl; 2.) Et₃N / 1.) dioxane, room t, 1 h; 2.) DMF, water, 16 h

2: 86 percent / thermolysin / methanol; H₂O / 18 h / Ambient temperature; effect of the pH

With hydrogenchloride; triethylamine; thermolysin; In methanol; water;
DOI:10.1248/cpb.36.4345

Reference yield:

: 103802-00-2
Boc-Met-Asp-OH

: 5235-21-2
N-tert-butoxycarbonyl-L-tryptophyl->L-methionyl->L-α-aspartyl->L-phenylalanine amide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 3 N HCl; 2.) Et₃N / 1.) dioxane, room t, 1 h; 2.) DMF, water, 16 h

2: 86 percent / thermolysin / methanol; H₂O / 18 h / Ambient temperature; effect of the pH

With hydrogenchloride; triethylamine; thermolysin; In methanol; water;
DOI:10.1248/cpb.36.4345