6-(1-Methylethyl)-2(1H)-Pyridinone

Base Information

Chemical Name:6-(1-Methylethyl)-2(1H)-Pyridinone
CAS No.:62969-85-1
Molecular Formula:C8H11NO
Molecular Weight:137.17900
Hs Code.:2933399090
Mol file:62969-85-1.mol

Synonyms:6-Isopropyl-2-pyridon;6-Isopropyl-1H-pyrimidin-2,4-dion;6-isopropyluracil;6-isopropyl-1H-pyrimidine-2,4-dione;

Suppliers and Price of 6-(1-Methylethyl)-2(1H)-Pyridinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-propan-2-yl-1H-pyridin-2-one
10mg
$ 45.00

Crysdot
6-Isopropylpyridin-2(1H)-one 95+%
25g
$ 1409.00

Crysdot
6-Isopropylpyridin-2(1H)-one 95+%
10g
$ 842.00

Crysdot
6-Isopropylpyridin-2(1H)-one 95+%
5g
$ 559.00

Chemenu
6-Isopropylpyridin-2(1H)-one 95%
5g
$ 528.00

Chemenu
6-Isopropylpyridin-2(1H)-one 95%
10g
$ 795.00

ChemBridge Corporation
6-isopropyl-2-pyridinol 95%
1 g
$ 300.00

Alichem
6-Isopropylpyridin-2(1H)-one
10g
$ 1346.33

Alichem
6-Isopropylpyridin-2(1H)-one
5g
$ 906.78

AccelPharmtech
6-(1-methylethyl)-2(1H)-Pyridinone 97.00%
5G
$ 1690.00

Total 5 raw suppliers

Chemical Property of 6-(1-Methylethyl)-2(1H)-Pyridinone

Chemical Property:

Melting Point:129-130 °C
Boiling Point:287-288 °C
PKA:11.92±0.10(Predicted)
PSA：33.12000
Density:1.011±0.06 g/cm3(Predicted)
LogP:1.91060
Storage Temp.:2-8°C

Purity/Quality:

99% ^*data from raw suppliers

6-propan-2-yl-1H-pyridin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-(1-Methylethyl)-2(1H)-Pyridinone

There total 9 articles about 6-(1-Methylethyl)-2(1H)-Pyridinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 78-82-0
Isobutyronitrile

: 503-64-0
(Z)-but-2-enoic acid

: 62969-85-1
6-isopropyl-2(1H)-pyridinone

Guidance literature:: (Z)-but-2-enoic acid; With n-butyllithium; diethylamine; In tetrahydrofuran; at 0 ℃; for 0.5h;

Isobutyronitrile; In tetrahydrofuran; at -78 - 20 ℃; for 24h;
DOI:10.1055/s-1999-2763

Reference yield: 13.0%

: 78-82-0
Isobutyronitrile

: 107-93-7
(E)-but-2-enoic acid

: 62969-85-1
6-isopropyl-2(1H)-pyridinone

Guidance literature:: (E)-but-2-enoic acid; With lithium diethylamide; In tetrahydrofuran; at 0 ℃; for 0.5h;

Isobutyronitrile; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1055/s-2000-6254

Reference yield:

: 1530-88-7
pyrrolidine-1-carbonitrile

: 62969-85-1
6-isopropyl-2(1H)-pyridinone

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydride / tetrahydrofuran; paraffin / 20 h / Ambient temperature

2: xylene / 72 h / Heating

With potassium hydride; In tetrahydrofuran; paraffin; xylene;
DOI:10.1021/ja00522a052