N-(2-Hydroxy-4,5-dimethylphenyl)acetamide

Base Information

Chemical Name:N-(2-Hydroxy-4,5-dimethylphenyl)acetamide
CAS No.:63494-69-9
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:
DSSTox Substance ID:DTXSID40505180
Nikkaji Number:J71.631F
Wikidata:Q82360119

Synonyms:N-(2-Hydroxy-4,5-dimethylphenyl)acetamide;63494-69-9;SCHEMBL4958829;DTXSID40505180;DWXIXAXNKTUUPM-UHFFFAOYSA-N;AKOS022640260

Suppliers and Price of N-(2-Hydroxy-4,5-dimethylphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(2-Hydroxy-4,5-dimethylphenyl)acetamide

Chemical Property:

PSA：52.82000
LogP:2.61690
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:193

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1C)O)NC(=O)C

Technology Process of N-(2-Hydroxy-4,5-dimethylphenyl)acetamide

There total 8 articles about N-(2-Hydroxy-4,5-dimethylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: N-(3,4-dimethylphenoxy)acetamide

: 63494-69-9
N-(2-hydroxy-4,5-dimethylphenyl)acetamide

Guidance literature:: With tris(acetonitrile)(η5-pentamethylcyclopentadienyl)rhodium(III) hexafluoroantimonate; sodium acetate; 5,6,7,8-tetrafluoro-1,2,3,4-tetrahydro-1,4-epoxynaphthalene; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere; Sealed tube; Schlenk technique;
DOI:10.1021/jacs.7b02725

Reference yield: 73.0%

: 123765-70-8
N-(2-iodo-4,5-dimethylphenyl)acetamide

: 63494-69-9
N-(2-hydroxy-4,5-dimethylphenyl)acetamide

Guidance literature:: With copper(II) oxide; water; caesium carbonate; at 100 ℃; for 3h; Green chemistry;
DOI:10.1039/c3ra46820h

Reference yield:

: 6623-41-2
2-amino-4,5-dimethylphenol

: 75-36-5
acetyl chloride

: 63494-69-9
N-(2-hydroxy-4,5-dimethylphenyl)acetamide

Guidance literature:: 2-amino-4,5-dimethylphenol; acetyl chloride; With sodium hydrogencarbonate; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

With hydrogenchloride; In water; pH=4 - 5;