(3-Iodophenyl)(trimethyl)silane

Base Information

• Chemical Name: (3-Iodophenyl)(trimethyl)silane
• CAS No.: 63520-49-0
• Molecular Formula: C9H13ISi
• Molecular Weight: 276.192
• DSSTox Substance ID: DTXSID70493884
• Wikidata: Q82340874
• Mol file: 63520-49-0.mol

Synonyms:(3-Iodophenyl)(trimethyl)silane;63520-49-0;SCHEMBL8722312;DTXSID70493884;HVBLGOGCBCNKEX-UHFFFAOYSA-N;1-Iodo-3-trimethylsilanyl-benzene

Chemical Property of (3-Iodophenyl)(trimethyl)silane

Chemical Property:

• PSA: 0.00000
• LogP: 2.83640
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 275.98312
• Heavy Atom Count: 11
• Complexity: 128

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)C1=CC(=CC=C1)I

Technology Process of (3-Iodophenyl)(trimethyl)silane

There total 2 articles about (3-Iodophenyl)(trimethyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

chloro-trimethyl-silane (75-77-4) + 1,3-Diiodobenzene (626-00-6) → 1-Iod-3-(trimethylsilyl)benzol (63520-49-0)

Guidance literature:

1,3-Diiodobenzene; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1.16667h;

chloro-trimethyl-silane; In diethyl ether; hexane; at 20 ℃; for 4h;

Reference yield:

m-bis(trimethylsilyl)benzene (2060-89-1,34471-37-9) → 1-Iod-3-(trimethylsilyl)benzol (63520-49-0)

Guidance literature:

With iodine(I) bromide;

Reference yield: 95.0%

1-Iod-3-(trimethylsilyl)benzol (63520-49-0) + trimethylsilylacetylene (1066-54-2) → (3-Trimethylsilyl-phenylethinyl)-trimethylsilan (16116-86-2)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1021/ol401375n

upstream raw materials:

m-bis(trimethylsilyl)benzene

chloro-trimethyl-silane

1,3-Diiodobenzene

Downstream raw materials:

1-Bromo-3-iodobenzene

(3-iodophenyl)(phenyl)methanol

C₁₇H₁₈OSi

3-(trimethylsilyl)phenylacetylene